Items where Author is "Chantry, Andrew"

Dudey, Ashley P., Rigby, Jake M., Hughes, Gregory R., Stephenson, G. Richard ORCID: https://orcid.org/0000-0003-1487-9178, Storr, Thomas E., Chantry, Andrew and Hemmings, Andrew M. ORCID: https://orcid.org/0000-0003-3053-3134 (2024) Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases. Journal of Enzyme Inhibition and Medicinal Chemistry, 39 (1). ISSN 1475-6366

Hughes, Gregory R., Dudey, Ashley P., Hemmings, Andrew M. ORCID: https://orcid.org/0000-0003-3053-3134 and Chantry, Andrew (2021) Frontiers in PROTACs. Drug Discovery Today, 26 (10). pp. 2377-2383. ISSN 1359-6446

Wahl, Lloyd C., Watt, Jessica E., De Bourcier, Danielle, Chantry, Andrew and Blumenschein, Tharin M. A. ORCID: https://orcid.org/0000-0002-4932-5178 (2020) WW domains from WWP2 E3 ubiquitin ligase recognise Oct4 and Smad7 peptides. Biophysical Journal, 118 (3). 182a. ISSN 0006-3495

Wahl, Lloyd C., Watt, Jessica E., Yim, Hiu Tung, De Bourcier, Danielle, Tolchard, James, Soond, Surinder, Blumenschein, Tharin ORCID: https://orcid.org/0000-0002-4932-5178 and Chantry, Andrew (2019) Smad7 binds differently to individual and tandem WW3 and WW4 domains of WWP2 ubiquitin ligase isoforms. International Journal of Molecular Sciences, 20 (19). ISSN 1661-6596

Watt, Jessica, Hughes, Gregory, Walpole, Samuel, Monaco, Serena, Stephenson, G. ORCID: https://orcid.org/0000-0003-1487-9178, Bulman Page, Philip, Hemmings, Andrew ORCID: https://orcid.org/0000-0003-3053-3134, Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639 and Chantry, Andrew (2018) Discovery of small molecule WWP2 ubiquitin ligase inhibitors. Chemistry - A European Journal, 24 (67). pp. 17677-17680. ISSN 0947-6539

Kaur, Gagandeep, Li, Caiyun Grace, Chantry, Andrew, Stayner, Cherie, Horsfield, Julia and Eccles, Michael R. (2018) SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma. Oncotarget, 9 (42). pp. 26852-26867. ISSN 1949-2553

Soond, Surinder M., Smith, Paul G., Wahl, Lloyd, Swingler, Tracey E., Clark, Ian M., Hemmings, Andrew M. ORCID: https://orcid.org/0000-0003-3053-3134 and Chantry, Andrew (2013) Novel WWP2 ubiquitin ligase isoforms as potential prognostic markers and molecular targets in cancer. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (12). pp. 2127-2135. ISSN 0925-4439

Leivonen, Suvi-Katri, Lazaridis, Konstantinos, Decock, Julie, Chantry, Andrew, Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 and Kähäri, Veli-Matti (2013) TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2. PLoS One, 8 (2). ISSN 1932-6203

Smith, Paul G., Tanaka, Hideo and Chantry, Andrew (2012) A novel co-operative mechanism linking TGFb and Lyn Kinase activation to imatinib resistance in chronic myeloid leukaemia cells. Oncotarget, 3 (5). pp. 518-524. ISSN 1949-2553

Soond, Surinder M. and Chantry, Andrew (2011) How ubiquitination regulates the TGF-β signalling pathway: New insights and new players. BioEssays, 33 (10). pp. 749-758. ISSN 1521-1878

Chantry, Andrew (2011) WWP2 ubiquitin ligase and its isoforms: New biological insight and promising disease targets. Cell Cycle, 10 (15). pp. 2437-2439. ISSN 1538-4101

Cutts, Anthony J., Soond, Surinder M., Powell, Steve and Chantry, Andrew (2011) Early phase TGFβ receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses. International Journal of Biochemistry & Cell Biology, 43 (4). pp. 604-612. ISSN 1878-5875

Soond, S. M. and Chantry, A. (2011) Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT. Oncogene, 30. pp. 2451-2462. ISSN 0950-9232

Swingler, TE, Culley, KL, Nicolas, F, Soond, S, Abu-Elmagd, M, Boot-Handford, RP, Young, DA, Chantry, A, Munsterberg, A ORCID: https://orcid.org/0000-0002-4577-4240 and Hajihosseini, M (2010) 066 Identification and Characterisation of Micrornas Involved in Chondrocyte Differentiation and Osteoarthritis. Working Paper. UNSPECIFIED.

Pais, Helio, Nicolas, Francisco Esteban, Soond, Surinder M., Swingler, Tracey E., Clark, Ian M., Chantry, Andrew, Moulton, Vincent ORCID: https://orcid.org/0000-0001-9371-6435 and Dalmay, Tamas ORCID: https://orcid.org/0000-0003-1492-5429 (2010) Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level. RNA, 16 (3). pp. 489-494. ISSN 1355-8382

Traka, Maria, Gasper, Amy V., Melchini, Antonietta, Bacon, James R., Needs, Paul W., Frost, Victoria, Chantry, Andrew, Jones, Alexandra M. E., Ortori, Catharine A., Barrett, David A., Ball, Richard Y., Mills, Robert D. and Mithen, Richard F. (2008) Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS One, 3 (7). ISSN 1932-6203

Frost, Victoria, Grocott, Timothy ORCID: https://orcid.org/0000-0002-6321-401X, Eccles, Michael R. and Chantry, Andrew (2008) Self-regulated Pax gene expression and modulation by the TGFβ superfamily. Critical Reviews in Biochemistry and Molecular Biology, 43 (6). pp. 371-391. ISSN 1549-7798

Møller, Gigi M., Frost, Victoria, Melo, Junia V. and Chantry, Andrew (2007) Upregulation of the TGFbeta signalling pathway by Bcr-Abl: Implications for haemopoietic cell growth and chronic myeloid leukaemia. FEBS Letters, 581 (7). pp. 1329-1334. ISSN 0014-5793

Grocott, Timothy ORCID: https://orcid.org/0000-0002-6321-401X, Frost, Victoria, Maillard, Marjorie, Johansen, Terje, Wheeler, Grant N. ORCID: https://orcid.org/0000-0002-4335-8577, Dawes, Lucy J., Wormstone, I. Michael ORCID: https://orcid.org/0000-0002-6423-7766 and Chantry, Andrew (2007) The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter. Nucleic Acids Research, 35 (3). pp. 890-901. ISSN 0305-1048

Wicks, SJ, Grocott, T ORCID: https://orcid.org/0000-0002-6321-401X, Haros, K, Maillard, M, ten Dijke, PT and Chantry, A (2006) Reversible uniquitination regulates the Smad/TGF-beta signalling pathway. Biochemical Society Transactions, 34. pp. 761-763. ISSN 1470-8752

Wicks, Stephen J., Haros, Katherine, Maillard, Marjorie, Song, Ling, Cohen, Robert E., ten Dijke, Peter and Chantry, Andrew (2005) The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGFbeta signalling. Oncogene, 24 (54). pp. 8080-8084. ISSN 0950-9232

Wormstone, I. M. ORCID: https://orcid.org/0000-0002-6423-7766, Tamiya, S., Eldred, J. A., Lazaridis, K., Chantry, A., Reddan, J. R., Anderson, I. and Duncan, G. (2004) Characterisation of TGF-beta 2 signalling and function in a human lens cell line. Experimental Eye Research, 78 (3). pp. 705-714. ISSN 1096-0007

Oksvold, Morten P., Thien, Christine B. F., Widerberg, Jannicke, Chantry, Andrew, Huitfeldt, Henrik S. and Langdon, Wallace Y. (2004) UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain. Radiation Research, 161 (6). pp. 685-691. ISSN 1938-5404

Hall, Marie-Claire, Young, David A., Waters, Jasmine G., Rowan, Andrew D., Chantry, Andrew, Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 and Clark, Ian M. (2003) The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1. Journal of Biological Chemistry, 278 (12). pp. 10304-10313. ISSN 1083-351X

Oksvold, Morten P., Thien, Christine B. F., Widerberg, Jannicke, Chantry, Andrew, Huitfeldt, Henrik S. and Langdon, Wallace Y. (2003) Serine mutations that abrogate ligand-induced uniquitination and internalization of the EGF receptor do not affect c-Cb1 association with the receptor. Oncogene, 22. pp. 8509-8518. ISSN 1476-5594

Sweetman, Dylan, Smith, Terry, Farrell, Elizabeth R., Chantry, Andrew and Munsterberg, Andrea ORCID: https://orcid.org/0000-0002-4577-4240 (2003) The conserved glutamine rich region of chick csal1 and csal3 mediates protein interactions with other spalt family members - implications for Townes-Brocks syndrome. Journal of Biological Chemistry, 278 (8). pp. 6560-6566. ISSN 0021-9258

Leivonen, Suvi-Katri, Chantry, Andrew, Hakkinen, Lari, Han, Jiahuai and Kahari, Veli-Matti (2002) Smad3 mediates transforming growth factor-beta-induced collagenase-3 (MMP-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signalling pathways. Journal of Biological Chemistry, 277. pp. 46338-46346. ISSN 1083-351X

Abdel-Wahab, Nadia, Wicks, Stephen J., Mason, Roger M. and Chantry, Andrew (2002) Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240. Biochemical Journal, 362 (3). pp. 643-649. ISSN 0264-6021