Effectiveness of a theory-informed intervention to increase care home staff influenza vaccination rates: a cluster randomised controlled trial

Wright, David, Blacklock, Jeanette, Bion, Veronica, Birt, Linda, Clark, Allan, Griffiths, Alyn Wyn, Guillard, Cecile, Stirling, Susan, Jones, Andy, Holland, Richard, Jones, Liz, Katangwe-Chigamba, Thando, Seeley, Carys, Pitcher, Jennifer, Risebro, Helen, Scott, Sion, Wagner, Adam, Sims, Erika, Ahmed, Saiqa, Cook, Luke and Patel, Amrish (2025) Effectiveness of a theory-informed intervention to increase care home staff influenza vaccination rates: a cluster randomised controlled trial. Journal of Public Health. ISSN 1741-3842

Full text not available from this repository. (Request a copy)

Abstract

Background: Care home staff’s (CHS’s) influenza vaccination rate in England is 30%–40%, below the 75% WHO recommendation. We describe the effectiveness of a theory-informed and feasibility-tested intervention (in-home clinics; posters/videos to address vaccination hesitancy and care home financial incentives for uptake) to improve CHS vaccination rates. Method: Recruited care homes in England with CHS vaccination rates <40% were randomised at the home level for intervention or control. Assuming a change in CHS vaccinated from 55% to 75%, 20% attrition, and 90% power, we required 39 homes per arm. Monthly data were collected throughout flu season. The difference in vaccination rates between the arms was compared using the intention-to-treat principle and a random effect logistic regression model. Findings: The mean % vaccination rate was 28.6% in control (n = 35) and 32.7% in intervention (n = 35) [odds ratio (OR) = 1.29, 95% confidence interval (CI): 0.68–0.4, P = .435]. In a sub-analysis, including only homes receiving at least one clinic, control was 28.6% (n = 35) and intervention was 41.7% (n = 23) (OR = 2.08, 95% CI: 0.67–2.70, P = .045). Interpretation: No effect on vaccination status was demonstrated. Within homes receiving clinics, a significant increase was observed. Process evaluation evidence suggests that starting 3 months into the influenza season partially explains this. Further evaluation initiating FluCare earlier is warranted.

Item Type:	Article
Additional Information:	Data availability statement: The FluCare data and materials are available for secondary research purposes. In the first instance, requests should be directed to Dr Amrish Patel (amrish.patel@uea.ac.uk). Release of data may be subject to completion of a data-sharing agreement. Funding information: The FluCare project was funded by the National Institute for Health and Care Research (NIHR) Public Health Research Programme (NIHR133455). The views expressed are those of the author(s) and not necessarily those of the NIHR or the DHSC. A.P.W., University of East Anglia, is supported by the NIHR Applied Research Collaboration East of England at Cambridgeshire and Peterborough NHS Foundation Trust.
Faculty \ School:	Faculty of Social Sciences > School of Economics Faculty of Medicine and Health Sciences > Norwich Medical School Faculty of Social Sciences > School of Education and Lifelong Learning
UEA Research Groups:	Faculty of Social Sciences > Research Centres > Centre for Behavioural and Experimental Social Sciences Faculty of Social Sciences > Research Groups > Behavioural Economics Faculty of Social Sciences > Research Groups > Economic Theory Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Science > Research Groups > Statistics Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Social Sciences > Research Groups > Developmental Science Faculty of Medicine and Health Sciences > Research Groups > Health Economics
Depositing User:	LivePure Connector
Date Deposited:	31 Mar 2025 14:30
Last Modified:	01 Apr 2025 14:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/98906
DOI:	10.1093/pubmed/fdaf023

Actions (login required)

View Item