Foodborne bacterial pathogens: Genome-based approaches for enduring and emerging threats in a complex and changing world

Mather, Alison E., Gilmour, Matthew W., Reid, Stuart W. J. and French, Nigel P. (2024) Foodborne bacterial pathogens: Genome-based approaches for enduring and emerging threats in a complex and changing world. Nature Reviews Microbiology, 22 (9). pp. 543-555. ISSN 1740-1526

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Abstract

Foodborne illnesses pose a substantial health and economic burden, presenting challenges in prevention due to the diverse microbial hazards that can enter and spread within food systems. Various factors, including natural, political and commercial drivers, influence food production and distribution. The risks of foodborne illness will continue to evolve in step with these drivers and with changes to food systems. For example, climate impacts on water availability for agriculture, changes in food sustainability targets and evolving customer preferences can all have an impact on the ecology of foodborne pathogens and the agrifood niches that can carry microorganisms. Whole-genome and metagenome sequencing, combined with microbial surveillance schemes and insights from the food system, can provide authorities and businesses with transformative information to address risks and implement new food safety interventions across the food chain. In this Review, we describe how genome-based approaches have advanced our understanding of the evolution and spread of enduring bacterial foodborne hazards as well as their role in identifying emerging foodborne hazards. Furthermore, foodborne hazards exist in complex microbial communities across the entire food chain, and consideration of these co-existing organisms is essential to understanding the entire ecology supporting pathogen persistence and transmission in an evolving food system.

Item Type:	Article
Additional Information:	Funding Information: A.E.M. and M.W.G. are supported by the Biotechnology and Biological Sciences Research Council (BBSRC) Institute Strategic Programme Microbes and Food Safety BB/X011011/1 and its constituent project BBS/E/F/000PR13634 (Theme 1, Microbial threats from foods in established and evolving food systems). This work was also supported in part by BBSRC grants BB/V018221/1 and BB/X002985/1 (UK Food Safety Research Network). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Uncontrolled Keywords:	microbiology,immunology and microbiology(all),infectious diseases,sdg 2 - zero hunger,sdg 3 - good health and well-being,sdg 13 - climate action ,/dk/atira/pure/subjectarea/asjc/2400/2404
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	30 Nov 2024 01:44
Last Modified:	17 Dec 2024 01:41
URI:	https://ueaeprints.uea.ac.uk/id/eprint/97834
DOI:	10.1038/s41579-024-01051-z

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