Imaging of giant cell arteritis – recent advances

Owen, Claire E., Yates, Max ORCID: https://orcid.org/0000-0003-3977-8920, Liew, David F. L., Poon, Aurora M. T., Keen, Helen I., Hill, Catherine L. and Mackie, Sarah L. (2023) Imaging of giant cell arteritis – recent advances. Best Practice and Research: Clinical Rheumatology, 37 (1). ISSN 1521-6942

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Abstract

Imaging is increasingly being used to guide clinical decision-making in patients with giant cell arteritis (GCA). While ultrasound has been rapidly adopted in fast-track clinics worldwide as an alternative to temporal artery biopsy for the diagnosis of cranial disease, whole-body PET/CT is emerging as a potential gold standard test for establishing large vessel involvement. However, many unanswered questions remain about the optimal approach to imaging in GCA. For example, it is uncertain how best to monitor disease activity, given there is frequent discordance between imaging findings and conventional disease activity measures, and imaging changes typically fail to resolve completely with treatment. This chapter addresses the current body of evidence for the use of imaging modalities in GCA across the spectrum of diagnosis, monitoring disease activity, and long-term surveillance for structural changes of aortic dilatation and aneurysm formation and provides suggestions for future research directions.

Item Type: Article
Uncontrolled Keywords: angiography,computed tomography,diagnosis,giant cell arteritis,imaging,magnetic resonance imaging,monitoring,positron emission tomography,ultrasound,rheumatology ,/dk/atira/pure/subjectarea/asjc/2700/2745
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Centres > Population Health
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Depositing User: LivePure Connector
Date Deposited: 27 Aug 2024 14:30
Last Modified: 01 Sep 2024 06:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/96359
DOI: 10.1016/j.berh.2023.101827

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