Consensus criteria for chronic rhinosinusitis disease control:an international Delphi Study

Sedaghat, A. R., Fokkens, W. J., Lund, V. J., Hellings, P. W., Kern, R. C., Reitsma, S., Toppila-Salmi, S., Bernal-Sprekelsen, M., Mullol, J., Gevaert, P., Teeling, T., Alobid, I., Anselmo-Lima, W. T., Baroody, F. M., Cervin, A., Cohen, N. A., Constantinidis, J., De Gabory, L., Desrosiers, M., Harvey, R. J., Kalogjera, L., Knill, A., Landis, B. N., Meco, C., Philpott, C. M. ORCID: https://orcid.org/0000-0002-1125-3236, Ryan, D., Schlosser, R. J., Senior, B. A., Smith, T. L., Tomazic, P. V., Zhang, L. and Hopkins, C. (2023) Consensus criteria for chronic rhinosinusitis disease control:an international Delphi Study. Rhinology, 61 (6). pp. 519-530. ISSN 0300-0729

Microsoft Word (OpenXML) (manuscript 090623) - Accepted Version Download (154kB)

Abstract

Background: Chronic rhinosinusitis (CRS) disease control is a global metric of disease status for CRS. While there is broad acceptance that it is an important treatment goal, there has been inconsistency in the criteria used to define CRS control. The objective of this study was to identify and develop consensus around essential criteria for assessment of CRS disease control. Methods: Modified Delphi methodology consisting of three rounds to review a list of 24 possible CRS control criteria developed by a 12-person steering committee. The core authorship of the multidisciplinary EPOS 2020 guidelines was invited to participate. Results: Thirty-two individuals accepted the invitation to participate and there was no dropout of participants throughout the entire study (3 rounds). Consensus essential criteria for assessment of CRS control were: overall symptom severity, need for CRS-related systemic corticosteroids in the prior 6 months, severity of nasal obstruction, and patient-reported CRS control. Near-consensus items were: nasal endoscopy findings, severity of smell loss, overall quality of life, impairment of normal activities and severity of nasal discharge. Participants’ comments provided insights into caveats of, and disagreements related to, near-consensus items. Conclusions: Overall symptom severity, use of CRS-related systemic corticosteroids, severity of nasal obstruction, and patient-reported CRS control are widely agreed upon essential criteria for assessment of CRS disease control. Consideration of near-consensus items to assess CRS control should be implemented with their intrinsic caveats in mind. These identified consensus CRS control criteria, together with evidence-based support, will provide a foundation upon which CRS control criteria with wide-spread acceptance can be developed.

Item Type:	Article
Uncontrolled Keywords:	delphi,epos,chronic rhinosinusitis; control,consensus,outcome measure,otorhinolaryngology ,/dk/atira/pure/subjectarea/asjc/2700/2733
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	22 Dec 2023 02:21
Last Modified:	22 Dec 2023 02:21
URI:	https://ueaeprints.uea.ac.uk/id/eprint/94028
DOI:	10.4193/Rhin23.335

Downloads

Actions (login required)

View Item