Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021

Blomquist, Paula B., Bridgen, Jessica, Bray, Neil, O'Connell, Anne Marie, West, Daniel, Groves, Natalie, Gallagher, Eileen, Utsi, Lara, Jarvis, Christopher I., Hardstaff, Jo L., Byers, Chloe, Metelmann, Soeren, Simons, David, Zaidi, Asad, Twohig, Katherine A., Savagar, Bethan, Løchen, Allesandra, Ryan, Cian, Wrenn, Katie, Saavedra-Campos, Maria, Abedin, Zahidul, Florence, Isaac, Cleary, Paul, Elson, Richard, Vivancos, Roberto and Lake, Iain R. (2022) Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021. Eurosurveillance, 27 (11). ISSN 1560-7917

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Abstract

When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omicron cases, alongside real-time surveillance and modelling of Omicron growth. SGTS was key to public health action (including case identification and incident management), and we share applied insights on how and when to use SGTS.

Item Type: Article
Uncontrolled Keywords: sars-cov-2,disease surveillance,s-gene target failure,covd-19,public health,omicron,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Science > School of Environmental Sciences
Depositing User: LivePure Connector
Date Deposited: 17 Mar 2022 13:30
Last Modified: 15 Apr 2022 00:52
URI: https://ueaeprints.uea.ac.uk/id/eprint/84092
DOI: 10.2807/1560-7917.ES.2022.27.11.2200143

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