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Butler, Christopher L., Bell, Ellen A. 
ORCID: https://orcid.org/0000-0001-7427-6331 and Taylor, Martin I. ORCID: https://orcid.org/0000-0002-3858-0712
(2021)
Removal of beneficial insertion effects prevent the long-term persistence of transposable elements within simulated asexual populations.
BMC Genomics, 22.
ISSN 1471-2164
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Abstract
Background: Transposable elements are significant components of most organism’s genomes, yet the reasons why their abundances vary significantly among species is poorly understood. A recent study has suggested that even in the absence of traditional molecular evolutionary explanations, transposon proliferation may occur through a process known as ‘transposon engineering’. However, their model used a fixed beneficial transposon insertion frequency of 20%, which we believe to be unrealistically high. Results: Reducing this beneficial insertion frequency, while keeping all other parameters identical, prevented transposon proliferation. Conclusions: We conclude that the author’s original findings are better explained through the action of positive selection rather than ‘transposon engineering’, with beneficial insertion effects remaining important during transposon proliferation events.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding information: CB was supported by a Natural Environment Research Council (NERC) and EnvEast doctoral training partnership (DTP) grant [grant number NE/L002582/1] and EB was supported by a BBSRC grant [BB/R017174/1] awarded to MT. The funders had no role in the design of the study, analysis, interpretation of the data or the writing of the manuscript. |
| Uncontrolled Keywords: | c-value,genome ecology,in-silico model,positive selection,transposon proliferation,biotechnology,genetics ,/dk/atira/pure/subjectarea/asjc/1300/1305 |
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| UEA Research Groups: | Faculty of Science > Research Groups > Organisms and the Environment Faculty of Science > Research Groups > Biosciences Teaching and Education Research Faculty of Science > Research Centres > Centre for Ecology, Evolution and Conservation |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 12 Jan 2021 00:54 |
| Last Modified: | 17 Oct 2024 09:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/78151 |
| DOI: | 10.1186/s12864-021-07569-3 |
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