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ToolsLiu, Dandan, Zhang, Chuanwei, Dong, Guirong, Xu, Chao, Liu, Dianzi, Lv, Yuan, Zhong, Bin and Wang, Bin (2019) Temperature-controlled electrospinning of EVOH nanofibre mats encapsulated with Ag, CuO, and ZnO particles for skin wound dressing. Materials Research Express, 6 (1). ISSN 2053-1591
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Abstract
To treat skin burns, a new wound dressing, nanofibre mats with metal or metal oxide nanoparticles (Ag, CuO, and ZnO), was fabricated using the electrospinning technique. During a therapeutic process, the antibacterial ability and bio-compatibility of a new dressing material are of major concern. To expound the characteristics of ethylene vinyl alcohol (EVOH) nanofibre mats encapsulated with metal or metal oxide nanoparticles, denoted as Ag-EVOH, CuO-EVOH, and ZnO-EVOH, for use as new wound dressing materials, we investigated the suitable processing parameters to fabricate these materials, such as the voltage, tip-to-collector distance, concentration of the solution, and effect of environmental temperature. The antibacterial ability and bio-compatibility of Ag-EVOH, CuO-EVOH, and ZnO-EVOH were then tested and quantified. The outcomes show that the most suitable temperature for the fabrication of the materials is 40 °C (±3 °C). The antibacterial experiment results indicate that 0.08 g/ml of metal/metallic oxide shows the highest antibacterial ability toward Staphylococcus aureus. Furthermore, the largest diameters of the bacteriostatic loops of the three types of nanofibre mats, i.e. Ag-EVOH, CuO-EVOH, and ZnO-EVOH, are 5.89, 5.21, and 4.12 mm, respectively. Finally, the cell proliferations on the three nanofibre mats show a similar growth trend.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | antibacterial ability,cell proliferation,electrospinning,nanoparticles,temperature,electronic, optical and magnetic materials,biomaterials,surfaces, coatings and films,polymers and plastics,metals and alloys ,/dk/atira/pure/subjectarea/asjc/2500/2504 |
| Faculty \ School: | Faculty of Science > School of Mathematics (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Sustainable Energy Faculty of Science > Research Groups > Materials, Manufacturing & Process Modelling |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 27 Sep 2018 08:30 |
| Last Modified: | 16 Dec 2024 01:28 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/68372 |
| DOI: | 10.1088/2053-1591/aae467 |
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