Which frail older people are dehydrated? The UK DRIE study

Hooper, Lee ORCID: https://orcid.org/0000-0002-7904-3331, Bunn, Diane, Downing, Alice, Jimoh, Florence, Groves, Joyce, Free, Carol, Cowap, Vicky, Potter, John, Hunter, Paul ORCID: https://orcid.org/0000-0002-5608-6144 and Shepstone, Lee (2016) Which frail older people are dehydrated? The UK DRIE study. The Journal of Gerontology: Medical Sciences, 71 (10). pp. 1341-1347.

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Abstract

Background: Water-loss dehydration in older people is associated with increased mortality and disability. We aimed to assess the prevalence of dehydration in older people living in UK long-term care, and associated cognitive, functional and health characteristics.  Methods: The Dehydration Recognition In our Elders (DRIE) cohort study included people ≥65 years living in long-term care without heart or renal failure. In a cross-sectional baseline analysis we assessed serum osmolality, previously suggested dehydration risk factors, general health, markers of continence, cognitive and functional health, nutrition status and medications. Univariate linear regression was used to assess relationships between participant characteristics and serum osmolality, then associated characteristics entered into stepwise backwards multivariate linear regression.   Results: DRIE included 188 residents (mean age 86 years, 66% women) of whom 20% were dehydrated (serum osmolality >300mOsm/kg). Linear and logistic regression suggested that renal, cognitive and diabetic status were consistently associated with serum osmolality and odds of dehydration, while potassium-sparing diuretics, sex, number of recent health contacts, and bladder incontinence were sometimes associated. Thirst was not associated with hydration status.  Conclusions: DRIE found high prevalence of dehydration in older people living in UK long-term care, reinforcing the proposed association between cognitive and renal function and hydration. Dehydration is associated with increased mortality and disability in older people, but trials to assess effects of interventions to support healthy fluid intakes in older people living in residential care are needed to enable us to formally assess causal direction and any health benefits of increasing fluid intakes.

Item Type:	Article
Uncontrolled Keywords:	dehy,aged,osmolar concentration,dementia ,diabetes mellitus,glomerular filtration rate ,residential facilities,risk factors,long-term care,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Health Promotion Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Social Sciences > Research Centres > Water Security Research Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	Pure Connector
Date Deposited:	01 Dec 2015 07:28
Last Modified:	19 Oct 2023 01:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/55535
DOI:	10.1093/gerona/glv205

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