Are bisphosphonates effective in the treatment of osteoarthritis pain?:A meta-analysis and systematic review

Davis, Alison J, Smith, Toby O ORCID: https://orcid.org/0000-0003-1673-2954, Hing, Caroline B and Sofat, Nidhi (2013) Are bisphosphonates effective in the treatment of osteoarthritis pain?:A meta-analysis and systematic review. PLoS One, 8 (9). ISSN 1932-6203

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Abstract

Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint replacement for larger joints are the standard of care. In light of several recent studies reporting the use of bisphosphonates for OA treatment, our work aimed to evaluate published literature to assess the effectiveness of bisphosphonates in OA treatment.

Item Type:	Article
Additional Information:	© 2013 Davis et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This work was supported by The Rosetrees' Trust, the National Institute for Health Research (NIHR) Comprehensive Local Research Network (CLRN), and The Wellcome Trust Value in People Award to Alison Davis.
Faculty \ School:	Faculty of Medicine and Health Sciences > School of Rehabilitation Sciences (former - to 2014) Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Rehabilitation Faculty of Medicine and Health Sciences > Research Groups > Health Promotion Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 14:44
Last Modified:	19 Oct 2023 01:15
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46973
DOI:	10.1371/journal.pone.0072714

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