Bew, Sean P., Brimage, Rebecca A., Hughes, David L., Legentil, Laurent, Sharma, Sunil V. and Wilson, Martin A. (2007) Expedient synthesis of substituted (diphenylphosphinoylmethyl)benzenes. The Journal of Organic Chemistry, 72 (7). pp. 2655-2658.
Full text not available from this repository. (Request a copy)Abstract
An efficient protocol for the synthesis of structurally diverse (diphenylphosphinoylmethyl)benzenes is described. The reaction employs readily available carboxylic acids, chlorodiphenylphosphine, and water as the reagents. A 97% reduction in the reaction times and substantially higher yields of products result, up to a 60% increase, if the reactions are performed under microwave irradiation. The first examples of transition-metal-catalyzed reactions applied to 4-bromo-1,3-bis(diphenylphosphinoylmethyl)benzene are also reported. © 2007 American Chemical Society.
Item Type: | Article |
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Faculty \ School: | Faculty of Science > School of Chemistry (former - to 2024) Faculty of Science > School of Chemical Sciences and Pharmacy (former - to 2009) |
UEA Research Groups: | Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017) |
Related URLs: | |
Depositing User: | Rachel Smith |
Date Deposited: | 15 Feb 2011 10:07 |
Last Modified: | 06 Feb 2025 02:41 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/21371 |
DOI: | 10.1021/jo062114k |
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