Evaluation of the Wisdom Enhancement Timeline approach for post-stroke depression using a single-case experimental design

Hassan, Ercan Timur, Gracey, Fergus and Blake, Joshua (2025) Evaluation of the Wisdom Enhancement Timeline approach for post-stroke depression using a single-case experimental design. Behavioural and Cognitive Psychotherapy. ISSN 1352-4658

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Abstract

Background: Approximately 24% of stroke survivors develop post-stroke depression (PSD), which is associated with poor psychological recovery, identity disruption, and reduced self-esteem. Psychological interventions often fail to address these broader challenges. The Wisdom Enhancement Timeline technique, which facilitates autobiographical reflection, has shown promise for depression in older adults. It has not yet been studied in a post-stroke population. Aims: This study evaluated the effectiveness of the Wisdom Enhancement Timeline technique in stroke. It was hypothesised that wisdom would improve first, followed by identity/self-esteem and mood. Method: A multiple-baseline single-case experimental design (SCED) was used across three stroke survivors. Daily visual analogue scale (VAS) ratings measured mood, identity, self-esteem, and wisdom during the trial. The Patient Health Questionnaire-9 (PHQ-9) measured depressive symptoms at pre- and post-intervention. Visual analysis, Tau-U, generalised least squares regression (adjusting for autocorrelation), and piecewise regression evaluated intervention effects. Results: Improvements were observed across all participants and outcomes. Tau-U analysis indicated small-to-large effect sizes across outcomes (effect size range: 0.30–0.92). Breakpoints confirmed wisdom improved first, followed by identity/self-esteem and mood last. Regression confirmed significant level shifts across all outcomes. All participants showed clinically meaningful reductions in PHQ-9 scores, operationalised as a shift from pre-intervention scores above 10 to post-intervention scores below 10. Conclusions: Wisdom-based interventions could be beneficial in a stroke population, promoting improvements in mood, identity coherence, self-esteem and wisdom. The Wisdom Enhancement Timeline technique shows promise for PSD treatment, although further research is needed to validate these effects.

Item Type: Article
Additional Information: Data availability statement: The data that support the findings of this study are available from the corresponding author, E.H., upon reasonable request.
Uncontrolled Keywords: cbt,depression,identity,stroke,identity,depression,stroke,clinical psychology ,/dk/atira/pure/subjectarea/asjc/3200/3203
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Mental Health and Social Care (fka Lifespan Health)
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Depositing User: LivePure Connector
Date Deposited: 07 Nov 2025 10:30
Last Modified: 14 Nov 2025 10:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/100927
DOI: 10.1017/S1352465825101124

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