Items where Research Group is "Synthetic and Medicinal Chemistry

A

Adjei, Silas, Amponsah, Isaac Kingsley, Ekuadzi, Edmund, Hamilton, Christopher, Gavrilovic, Jelena, Dillon, Oliver, El-Demerdash, Amr and Asante-Kwatia, Evelyn (2025) Assessment of wound healing properties of medicinal plants: The case of Berlinia confusa. Natural Product Communications, 20 (1). ISSN 1934-578X

Alanazi, Budur N., Alsahli, Ahad O., Remiro-Buenamañana, Sonia, Díaz-Moscoso, Alejandro, Alkorbi, Faeza H., Alsaiari, Norah A., Marrett-Munro, Conor, Chambrier, Isabelle, Hughes, David L., Coles, Simon J., Tizzard, Graham J. and Cammidge, Andrew Neil (2025) A family of symmetrical and unsymmetrical aza-dipyrromethenes and aza-BODIPYs with through-bond and face-to-face p‐-interaction between termini. Chemistry – A European Journal, 31 (50). ISSN 0947-6539

B

Bew, Sean P., Stephenson, G. Richard, Horil Roy, Deeptee, Gardiner, William and Martinez Lozano, Luis (2025) Mechanochemical Route to Upper Rim Tetrafunctionalised Prochiral and Inherently Chiral Calix[4]arenes.

Bidula, Stefan, Piyasirananda, Waraporn, Bielecka, Hanna, Bibič, Lučka, Beekman, Andrew and Stokes, Leanne (2025) Screening herbal and natural product libraries to aid discovery of novel allosteric modulators of human P2X7. Purinergic Signalling, 21 (2). 365–379. ISSN 1573-9538

Bressan, Giovanni, Chambrier, Isabelle, Cammidge, Andrew N. and Meech, Stephen R. (2025) Symmetry-breaking charge-separation in a subphthalocyanine dimer resolved by two-dimensional electronic spectroscopy. The Journal of Physical Chemistry C, 129 (2). 1069–1077. ISSN 1932-7447

C

Chambrier, Isabelle, Fotev, Valentin, Hughes, David L. and Cammidge, Andrew N. (2025) Design and synthesis of a sterically locked, highly distorted phthalocyanine and observation of all possible stereoisomers. Journal of Porphyrins and Phthalocyanines, 29 (03n04). pp. 528-533. ISSN 1088-4246

D

Douglas-Walker, Thomas E., Ashworth, Eleanor K., Stockett, Mark H., Daly, Francis C., Chambrier, Isabelle, Esposito, Vincent J., Gerlach, Marius, Zheng, Angel, Palotás, Julianna, Cammidge, Andrew N., Campbell, Ewen K., Brünken, Sandra and Bull, James N. (2025) Vibrational and electronic spectroscopy of 2-cyanoindene cations. ACS Earth and Space Chemistry, 9 (1). 134–145. ISSN 2472-3452

Duan, Zehui, Wei, Jiaao, Carr, Stephen B., Ramirez, Miguel, Evans, Rhiannon M., Ash, Philip A., Rodriguez-Macia, Patricia, Sachdeva, Amit and Vincent, Kylie A. (2025) Cyanophenylalanine as an infrared probe for iron–sulfur cluster redox state in multicenter metalloenzymes. ChemBioChem, 26 (14). ISSN 1439-4227

E

Elgohary, Alaa M., Elfiky, Abdo A., Pereira, Florbela, Gamal El-Din, Mariam I., Tammam, Mohamed A., Aouidate, Adnane and El-Demerdash, Amr (2025) Investigating the structure-activity relationship of laulimalides marine macrolides as promising inhibitors for SARS-CoV-2 main Protease (Mpro). Journal of Computational Biophysics and Chemistry, 24 (4). pp. 403-419. ISSN 2737-4165

Esfahani, Mohammadreza Haftbaradaran, Bergua, Fernando, Delso, Ignacio, Lafuente, Carlos and Artal, Manuela (2025) Geraniol:l-menthol eutectic mixtures; thermophysical properties and drug solubility. Sustainable Chemistry and Pharmacy, 46. ISSN 2352-5541

F

Fatima, Anam, Ashworth, Eleanor K., Fernandes, Isabelle, Cammidge, Andrew N., Bressan, Giovanni, Meech, Steve R. and Bull, James N. (2025) Ultrafast photophysics of the cyan fluorescent protein chromophore in solution. Physical Chemistry Chemical Physics, 27 (18). pp. 9407-9416. ISSN 1463-9076

Fatima, Anam, Chakraborty, Pratip, Xu, Xinyue, Jones, Garth A., Chambrier, Isabelle, Logan, Giorgia, Cammidge, Andrew N., Smith, Trevor, Hall, Christopher R. and Meech, Stephen R. (2025) Complex multistate photophysics of a rhodanine photoswitch. Angewandte Chemie-International Edition, 64 (37). ISSN 1433-7851

Ford, Jonathan J., Santos-Aberturas, Javier, Hems, Edward S., Sallmen, Joseph W., Bögeholz, Lena A. K., Polturak, Guy, Osbourn, Anne, Wright, Joseph A., Rodnina, Marina V., Vereecke, Danny, Francis, Isolde M. and Truman, Andrew W. (2025) Identification of the lydiamycin biosynthetic gene cluster in a plant pathogen guides structural revision and identification of molecular target. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 122 (21). ISSN 0027-8424

Furney, Isaac and Wright, Joseph (2025) Synthesis and characterisation of Mo(IV)-oxo dithiolenes: Formate dehydrogenase active site mimetics. Dalton Transactions. ISSN 1477-9226 (In Press)

J

Jo, Seohyun, El-Demerdash, Amr, Owen, Charlotte, Srivastava, Vikas, Wu, Dewei, Kikuchi, Shingo, Reed, James, Hodgson, Hannah, Harkess, Alex, Shu, Shengqiang, Plott, Chris, Jenkins, Jerry, Williams, Melissa, Boston, Lori-Beth, Lacchini, Elia, Qu, Tongtong, Goossens, Alain, Grimwood, Jane, Schmutz, Jeremy, Leebens-Mack, Jim and Osbourn, Anne (2025) Unlocking saponin biosynthesis in soapwort. Nature Chemical Biology, 21. 215–226. ISSN 1552-4450

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Malbon, Alexandra J., Czopek, Alicja, Beekman, Andrew M., Goddard, Zoë R., Boyle, Aileen, Ivy, Jessica R., Stewart, Kevin, Denham, Scott G., Simpson, Joanna P., Homer, Natalie Z., Walker, Brian R., Dhaun, Neeraj, Bailey, Matthew A. and Morgan, Ruth A. (2025) Carbonyl reductase 1: A novel regulator of blood pressure in Down syndrome. Bioscience Reports, 45 (2). pp. 157-170. ISSN 0144-8463

Morales Florez, Alejandro, Lockwood, Colin, Nash, Benjamin, Edwards, Marcus J., van Wonderen, Jessica H., Sachdeva, Amit, Butt, Julea N. and Clarke, Tom (2025) Extracellular catalysis of environmental substrates by Shewanella oneidensis MR-1 occurs via active sites on the C-terminal domains of MtrC. Protein Science, 34 (8). ISSN 1469-896X

Moustafa, Mahmoud, Aboelmaaty, Walaa S., Ebrahim, Weaam, Mekky, Reham Hassan, Tammam, Mohamed A., El-Demerdash, Amr and Zaghloul, Ahmed M. (2025) Chemical profiling of Lycium shawii via RP-HPLC-QTOF-MS and MS/MS: Unveiling its in-vivo wound-healing potential supported by molecular docking investigations. Fitoterapia, 185. ISSN 0367-326X

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Palmer, Leoni, Beekman, Andrew, Ganesan, A., MacDonald, Simon, Hatley, Richard and McDermott, Paul J. (2025) Crossing the divide: A transitional undergraduate research project in medicinal chemistry. Journal of Chemical Education, 102 (11). 4769–4775. ISSN 0021-9584

S

Soria-Lopez, Anton, Pecio, Łukasz, Saber, Fatema R., Abdel-Dayem, Shymaa I. A., Fayez, Shaimaa, Zengin, Gokhan, Kozachok, Solomiia, El-Demerdash, Amr, Garcia-Marti, Maria, Otero-Fuertes, Paz, Mejuto, Juan Carlos, Skalicka-Woźniak, Krystyna and Simal-Gandara, Jesus (2025) Metabolic profiling via UPLC/MS/MS and in vitro cholinesterase, amylase, glucosidase, and tyrosinase inhibitory effects of Carica papaya L. extracts reveal promising nutraceutical potential. Food Analytical Methods, 18. 57–74. ISSN 1936-976X

Stephenson, Michael J. and Brodelius, Peter E. (2025) Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis. Phytochemistry Reviews, 24 (6). pp. 4853-4916. ISSN 1568-7767

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Tammam, Mohamed A., Aouidate, Adnane, Mahmoud, Manar M., Gamal El-Din, Mariam I. and El-Demerdash, Amr (2025) Cortistatin and plakinamine steroidal alkaloids from the marine sponges of the genus Corticium: Insights into their chemistry, pharmacology, pharmacokinetics and structure activity relationships (SARs). RSC Advances, 15 (12). pp. 9092-9107. ISSN 2046-2069

Tammam, Mohamed A., Pereira, Florbela, Skellam, Elizabeth, Bidula, Stefan, Ganesan, A. and El-Demerdash, Amr (2025) The cytochalasans: Potent fungal natural products with application from bench to bedside. Natural Product Reports, 42 (5). pp. 788-841. ISSN 0265-0568

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van Wier, Suzanne P. and Beekman, Andrew M. (2025) Peptide design to control protein–protein interactions. Chemical Society Reviews, 54 (4). pp. 1684-1698. ISSN 0306-0012

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Wright, Joseph A., Haque, Farhana, Liborio, Leandro and Cottrell, Stephen P. (2025) Hydrogen radical chemistry at high-symmetry {2Fe2S} centers probed using a muonium surrogate. Inorganic Chemistry, 64 (10). 5053–5058. ISSN 0020-1669