Items where Research Group is "Synthetic and Medicinal Chemistry

Adjei, Silas, Amponsah, Isaac Kingsley, Ekuadzi, Edmund, Hamilton, Christopher, Gavrilovic, Jelena ORCID: https://orcid.org/0000-0002-5312-1784, Dillon, Oliver, El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 and Asante-Kwatia, Evelyn (2025) Assessment of wound healing properties of medicinal plants: The case of Berlinia confusa. Natural Product Communications, 20 (1). ISSN 1934-578X

Alanazi, Budur N., Alsahli, Ahad O., Remiro-Buenamañana, Sonia, Díaz-Moscoso, Alejandro, Alkorbi, Faeza H., Alsaiari, Norah A., Marrett-Munro, Conor, Chambrier, Isabelle, Hughes, David L., Coles, Simon J., Tizzard, Graham J. and Cammidge, Andrew Neil ORCID: https://orcid.org/0000-0001-7912-4310 (2025) A family of symmetrical and unsymmetrical aza-dipyrromethenes and aza-BODIPYs with through-bond and face-to-face p‐-interaction between termini. Chemistry – A European Journal, 31 (50). ISSN 0947-6539

Bew, Sean P. ORCID: https://orcid.org/0000-0002-9087-9463, Stephenson, G. Richard ORCID: https://orcid.org/0000-0003-1487-9178, Horil Roy, Deeptee, Gardiner, William and Martinez Lozano, Luis (2025) Mechanochemical Route to Upper Rim Tetrafunctionalised Prochiral and Inherently Chiral Calix[4]arenes.

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Piyasirananda, Waraporn, Bielecka, Hanna, Bibič, Lučka, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406 and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2025) Screening herbal and natural product libraries to aid discovery of novel allosteric modulators of human P2X7. Purinergic Signalling, 21 (2). 365–379. ISSN 1573-9538

Bressan, Giovanni ORCID: https://orcid.org/0000-0001-7801-8495, Chambrier, Isabelle, Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310 and Meech, Stephen R. ORCID: https://orcid.org/0000-0001-5561-2782 (2025) Symmetry-breaking charge-separation in a subphthalocyanine dimer resolved by two-dimensional electronic spectroscopy. The Journal of Physical Chemistry C, 129 (2). 1069–1077. ISSN 1932-7447

Chambrier, Isabelle, Fotev, Valentin, Hughes, David L. and Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310 (2025) Design and synthesis of a sterically locked, highly distorted phthalocyanine and observation of all possible stereoisomers. Journal of Porphyrins and Phthalocyanines, 29 (03n04). pp. 528-533. ISSN 1088-4246

Douglas-Walker, Thomas E., Ashworth, Eleanor K., Stockett, Mark H., Daly, Francis C., Chambrier, Isabelle, Esposito, Vincent J., Gerlach, Marius, Zheng, Angel, Palotás, Julianna, Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310, Campbell, Ewen K., Brünken, Sandra and Bull, James N. ORCID: https://orcid.org/0000-0003-0953-1716 (2025) Vibrational and electronic spectroscopy of 2-cyanoindene cations. ACS Earth and Space Chemistry, 9 (1). 134–145. ISSN 2472-3452

Duan, Zehui, Wei, Jiaao, Carr, Stephen B., Ramirez, Miguel, Evans, Rhiannon M., Ash, Philip A., Rodriguez-Macia, Patricia, Sachdeva, Amit and Vincent, Kylie A. (2025) Cyanophenylalanine as an infrared probe for iron–sulfur cluster redox state in multicenter metalloenzymes. ChemBioChem, 26 (14). ISSN 1439-4227

Elgohary, Alaa M., Elfiky, Abdo A., Pereira, Florbela, Gamal El-Din, Mariam I., Tammam, Mohamed A., Aouidate, Adnane and El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 (2025) Investigating the structure-activity relationship of laulimalides marine macrolides as promising inhibitors for SARS-CoV-2 main Protease (Mpro). Journal of Computational Biophysics and Chemistry, 24 (4). pp. 403-419. ISSN 2737-4165

Esfahani, Mohammadreza Haftbaradaran, Bergua, Fernando, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Lafuente, Carlos and Artal, Manuela (2025) Geraniol:l-menthol eutectic mixtures; thermophysical properties and drug solubility. Sustainable Chemistry and Pharmacy, 46. ISSN 2352-5541

Fatima, Anam ORCID: https://orcid.org/0000-0003-2388-4390, Ashworth, Eleanor K., Fernandes, Isabelle, Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310, Bressan, Giovanni ORCID: https://orcid.org/0000-0001-7801-8495, Meech, Steve R. ORCID: https://orcid.org/0000-0001-5561-2782 and Bull, James N. ORCID: https://orcid.org/0000-0003-0953-1716 (2025) Ultrafast photophysics of the cyan fluorescent protein chromophore in solution. Physical Chemistry Chemical Physics, 27 (18). pp. 9407-9416. ISSN 1463-9076

Fatima, Anam ORCID: https://orcid.org/0000-0003-2388-4390, Chakraborty, Pratip ORCID: https://orcid.org/0000-0002-0248-6193, Xu, Xinyue, Jones, Garth A., Chambrier, Isabelle, Logan, Giorgia, Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310, Smith, Trevor, Hall, Christopher R. and Meech, Stephen R. ORCID: https://orcid.org/0000-0001-5561-2782 (2025) Complex multistate photophysics of a rhodanine photoswitch. Angewandte Chemie-International Edition, 64 (37). ISSN 1433-7851

Ford, Jonathan J., Santos-Aberturas, Javier, Hems, Edward S., Sallmen, Joseph W., Bögeholz, Lena A. K., Polturak, Guy, Osbourn, Anne, Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Rodnina, Marina V., Vereecke, Danny, Francis, Isolde M. and Truman, Andrew W. (2025) Identification of the lydiamycin biosynthetic gene cluster in a plant pathogen guides structural revision and identification of molecular target. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 122 (21). ISSN 0027-8424

Furney, Isaac and Wright, Joseph ORCID: https://orcid.org/0000-0001-9603-1001 (2025) Synthesis and characterisation of Mo(IV)-oxo dithiolenes: Formate dehydrogenase active site mimetics. Dalton Transactions. ISSN 1477-9226 (In Press)

Hudson, Graham A., Pereira, Jose H., Winegar, Peter H., Fitzgerald, David M., Degiovanni, Andy, Chen, Xiaoyue, Zhao, Xixi, Astolfi, Maria C. T., Reed, James, El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955, Rejzek, Martin, Kikuchi, Shingo, Osbourn, Anne, Scheller, Henrik V., Adams, Paul D. and Keasling, Jay D. (2025) Enzymology and structural basis of glycosyltransferases involved in saponin C28 carboxylic acid O-d-fucosylation. JACS Au, 5 (12). 6011–6024. ISSN 2691-3704

Jo, Seohyun, El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955, Owen, Charlotte, Srivastava, Vikas, Wu, Dewei, Kikuchi, Shingo, Reed, James, Hodgson, Hannah, Harkess, Alex, Shu, Shengqiang, Plott, Chris, Jenkins, Jerry, Williams, Melissa, Boston, Lori-Beth, Lacchini, Elia, Qu, Tongtong, Goossens, Alain, Grimwood, Jane, Schmutz, Jeremy, Leebens-Mack, Jim and Osbourn, Anne (2025) Unlocking saponin biosynthesis in soapwort. Nature Chemical Biology, 21. 215–226. ISSN 1552-4450

Malbon, Alexandra J., Czopek, Alicja, Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406, Goddard, Zoë R. ORCID: https://orcid.org/0000-0002-7900-1553, Boyle, Aileen, Ivy, Jessica R., Stewart, Kevin, Denham, Scott G., Simpson, Joanna P., Homer, Natalie Z., Walker, Brian R., Dhaun, Neeraj, Bailey, Matthew A. and Morgan, Ruth A. (2025) Carbonyl reductase 1: A novel regulator of blood pressure in Down syndrome. Bioscience Reports, 45 (2). pp. 157-170. ISSN 0144-8463

Mekky, Reham Hassan, Faheem, Safaa A., Fawzy, Mariam H., Abo-El Fetoh, Mohammed E., Sweilam, Sherouk Hussein and El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 (2025) Natural Remedies for Hypercholesteremia. In: Natural Remedies in Disease Management and Treatment. CRC Press, pp. 191-222. ISBN 9781003464938

Morales Florez, Alejandro, Lockwood, Colin, Nash, Benjamin, Edwards, Marcus J., van Wonderen, Jessica H., Sachdeva, Amit, Butt, Julea N. ORCID: https://orcid.org/0000-0002-9624-5226 and Clarke, Tom ORCID: https://orcid.org/0000-0002-6234-1914 (2025) Extracellular catalysis of environmental substrates by Shewanella oneidensis MR-1 occurs via active sites on the C-terminal domains of MtrC. Protein Science, 34 (8). ISSN 1469-896X

Moustafa, Mahmoud, Aboelmaaty, Walaa S., Ebrahim, Weaam, Mekky, Reham Hassan, Tammam, Mohamed A., El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 and Zaghloul, Ahmed M. (2025) Chemical profiling of Lycium shawii via RP-HPLC-QTOF-MS and MS/MS: Unveiling its in-vivo wound-healing potential supported by molecular docking investigations. Fitoterapia, 185. ISSN 0367-326X

Palmer, Leoni, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ganesan, A., MacDonald, Simon, Hatley, Richard and McDermott, Paul J. (2025) Crossing the divide: A transitional undergraduate research project in medicinal chemistry. Journal of Chemical Education, 102 (11). 4769–4775. ISSN 0021-9584

Soria-Lopez, Anton, Pecio, Łukasz, Saber, Fatema R., Abdel-Dayem, Shymaa I. A., Fayez, Shaimaa, Zengin, Gokhan, Kozachok, Solomiia, El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955, Garcia-Marti, Maria, Otero-Fuertes, Paz, Mejuto, Juan Carlos, Skalicka-Woźniak, Krystyna and Simal-Gandara, Jesus (2025) Metabolic profiling via UPLC/MS/MS and in vitro cholinesterase, amylase, glucosidase, and tyrosinase inhibitory effects of Carica papaya L. extracts reveal promising nutraceutical potential. Food Analytical Methods, 18 (1). 57–74. ISSN 1936-976X

Stephenson, Michael J. ORCID: https://orcid.org/0000-0002-2594-1806 and Brodelius, Peter E. (2025) Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis. Phytochemistry Reviews, 24 (6). pp. 4853-4916. ISSN 1568-7767

Tammam, Mohamed A., Aouidate, Adnane, Mahmoud, Manar M., Gamal El-Din, Mariam I. and El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 (2025) Cortistatin and plakinamine steroidal alkaloids from the marine sponges of the genus Corticium: Insights into their chemistry, pharmacology, pharmacokinetics and structure activity relationships (SARs). RSC Advances, 15 (12). pp. 9092-9107. ISSN 2046-2069

Tammam, Mohamed A., Pereira, Florbela, Skellam, Elizabeth, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Ganesan, A. and El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 (2025) The cytochalasans: Potent fungal natural products with application from bench to bedside. Natural Product Reports, 42 (5). pp. 788-841. ISSN 0265-0568

Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Haque, Farhana, Liborio, Leandro and Cottrell, Stephen P. (2025) Hydrogen radical chemistry at high-symmetry {2Fe2S} centers probed using a muonium surrogate. Inorganic Chemistry, 64 (10). 5053–5058. ISSN 0020-1669

van Wier, Suzanne P. and Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406 (2025) Peptide design to control protein–protein interactions. Chemical Society Reviews, 54 (4). pp. 1684-1698. ISSN 0306-0012