Items where Research Group is "Pharmacology and Biological Chemistry

Akbar, Mohammad, Lukasewicz Ferreira, Pamela, Giorgetti, Melania, Stokes, Leanne and Morris, Christopher (2019) Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells. Beilstein Journal of Nanotechnology, 10. 2553–2562. ISSN 2190-4286

Beekman, Andrew M., Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O'Connell, Maria A., Angulo Alvarez, Jesus and Searcey, Mark (2019) Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design. Chemical Science, 10 (16). pp. 4502-4508. ISSN 2041-6520

Bennett, Sophie, Soriano-Laguna, Manuel, Bradley, Justin, Svistunenko, Dimitri A., Richardson, David, Gates, Andrew and Le Brun, Nicolas (2019) NosL is a dedicated copper chaperone for assembly of the Cuz center of nitrous oxide reductase. Chemical Science, 10 (19). pp. 4985-4993. ISSN 2041-6520

Bibic, Lucka, Druskis, Justinas, Walpole, Samuel, Angulo Alvarez, Jesus and Stokes, Leanne (2019) Bug off pain: An educational virtual reality game on spider venoms and chronic pain for public engagement. Journal of Chemical Education, 96 (7). pp. 1486-1490. ISSN 0021-9584

Bibic, Lucka, Herzig, Volker, King, Glenn and Stokes, Leanne (2019) Development of high-throughput fluorescent-based screens to accelerate discovery of P2X inhibitors from animal venoms. Journal of Natural Products, 82 (9). pp. 2559-2567. ISSN 0163-3864

Bidula, S., Dhuna, K., Helliwell, R., Stebbing, M. and Stokes, L. (2019) Herbaceous homicide:The Panax ginseng metabolite compound K accelerates caspase-3/7 activation and enhances macrophage cell death in a P2X7-dependent manner. British Journal of Pharmacology, 176 (16). p. 3028. ISSN 0007-1188

Bidula, Stefan, Dhuna, Kshitija, Helliwell, Ray and Stokes, Leanne (2019) Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages. Cell Death & Disease, 10. ISSN 2041-4889

Bidula, Stefan, Sexton, Darren and Schelenz, Silke (2019) Ficolins and the recognition of pathogenic microorganisms: An overview of the innate immune response and contribution of single nucleotide polymorphisms. Journal of Immunology Research, 2019. ISSN 2314-7156

Bidula, Stefan M., Cromer, Brett A., Walpole, Samuel, Angulo, Jesus and Stokes, Leanne (2019) Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7. Scientific Reports, 9. ISSN 2045-2322

Bradley, Justin M., Svistunenko, Dimitri A., Pullin, Jacob, Hill, Natalie, Stuart, Rhona K., Palenik, Brian, Wilson, Michael T., Hemmings, Andrew M., Moore, Geoffrey R. and Le Brun, Nick E. (2019) Reaction of O2 with a di-iron protein generates a mixed valent Fe2+/Fe3+ center and peroxide. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 116 (6). pp. 2058-2067. ISSN 1091-6490

Buchner, Markus, Garcia Calavia, Paula, Muhr, Verena, Kroninger, Anna, Baeumner, Antje, Hirsch, Thomas, Russell, David A. and Marin, Maria J. (2019) Photosensitiser functionalised luminescent upconverting nanoparticles for efficient photodynamic therapy of breast cancer cells. Photochemical & Photobiological Sciences, 18 (1). pp. 98-109. ISSN 1474-905X

Crack, Jason, Stewart, Melissa and Le Brun, Nicolas (2019) Generation of 34S-substituted protein-bound [4Fe-4S] clusters using 34S-L-cysteine. Biology Methods and Protocols, 4 (1). ISSN 2396-8923

Crack, Jason C. and Le Brun, Nicolas (2019) Mass spectrometric identification of [4Fe-4S](NO)x intermediates of nitric oxide sensing by regulatory iron-sulfur cluster proteins. Chemistry - A European Journal, 25 (14). pp. 3675-3684. ISSN 0947-6539

Dhuna, Kshitija, Felgate, Matthew, Bidula, Stefan, Walpole, Samuel, Bibic, Lucka, Cromer, Brett, Angulo, Jesus, Sanderson, Julie, Stebbing, Martin and Stokes, Leanne (2019) Ginsenosides act as positive modulators of P2X4 receptors. Molecular Pharmacology, 95 (2). pp. 210-221. ISSN 0026-895X

Dicarlo, Manuela, Teti, Gabriella, Verna, Giulio, Liso, Marina, Cavalcanti, Elisabetta, Sila, Annamaria, Raveenthiraraj, Sathuwarman, Mastronardi, Mauro, Santino, Angelo, Serino, Grazia, Lippolis, Antonio, Sobolewski, Anastasia, Falconi, Mirella and Chieppa, Marcello (2019) Quercetin exposure suppresses the inflammatory pathway in intestinal organoids from winnie mice. International Journal of Molecular Sciences, 20 (22). ISSN 1661-6596

Hamshaw, Isabel, Ajdarirad, Morvarid and Mueller, Anja (2019) The role of PKC and PKD in CXCL12 directed prostate cancer migration. Biochemical and Biophysical Research Communications, 519 (1). pp. 86-92. ISSN 0006-291X

Jenner, Leon P., Kurth, Julia M., van Helmont, Sebastian, Sokol, Katarzyna P., Reisner, Erwin, Dahl, Christiane, Bradley, Justin M., Butt, Julea N. and Cheesman, Myles (2019) Heme ligation and redox chemistry in two bacterial thiosulfate dehydrogenase (TsdA) enzyme. Journal of Biological Chemistry, 294 (47). pp. 18002-18014. ISSN 0021-9258

Kay, Kristine L., Hamilton, Chris J. and Le Brun, Nick E. (2019) Mass spectrometric studies of Cu(I)-binding to the N-terminal domains of B. subtilis CopA and influence of bacillithiol. Journal of Inorganic Biochemistry, 190. pp. 24-30. ISSN 0162-0134

Pellicer Martinez, Maria Teresa, Crack, Jason, Stewart, Melissa, Bradley, Justin, Svistunenko, Dimitri A., Johnston, Andrew, Cheesman, Myles, Todd, Jonathan and Le Brun, Nick (2019) Mechanisms of iron- and O2-sensing by the [4Fe-4S] cluster of the global iron regulator RirA. eLife, 8. ISSN 2050-084X

Stokes, Leanne (2019) Recording P2X Receptors Using Whole-Cell Patch Clamp from Native Monocytes and Macrophages. In: Purinergic Signaling. Purinergic Signaling . Springer (Humana Press), pp. 275-283. ISBN 978-1-4939-9716-9

Volbeda, Anne, Pellicer Martinez, Ma Teresa, Crack, Jason C., Amara, Patricia, Gigarel, Océane, Munnoch, John T., Hutchings, Matthew I., Darnault, Claudine, Le Brun, Nick E. and Fontecilla-Camps, Juan C. (2019) Crystal structure of the transcription regulator RsrR reveals a [2Fe-2S] cluster coordinated by Cys, Glu and His residues. Journal of the American Chemical Society, 141 (6). 2367–2375. ISSN 0002-7863

Wahl, Lloyd C., Watt, Jessica E., Yim, Hiu Tung, De Bourcier, Danielle, Tolchard, James, Soond, Surinder, Blumenschein, Tharin and Chantry, Andrew (2019) Smad7 binds differently to individual and tandem WW3 and WW4 domains of WWP2 ubiquitin ligase isoforms. International Journal of Molecular Sciences, 20 (19). ISSN 1661-6596

Wright, Phillip, Kelsall, Janet, Healing, Guy and Sanderson, Julie (2019) Differential expression of cyclin-dependent kinases in the adult human retina in relation to CDK inhibitor retinotoxicity. Archives of Toxicology, 93 (3). 659–671. ISSN 0340-5761