Items where Research Group is "Chemistry of Life Processes

A

Azmanova, Maria, Soldevila‐Barreda, Joan, Hani, Hira Bani, Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X, Pitto‐Barry, Anaïs, Picksley, Steven M. and Barry, Nicolas P. E. (2019) Anticancer activity of electron-deficient metal complexes against colorectal cancer in vitro models. ChemMedChem, 14 (22). pp. 1887-1893. ISSN 1860-7179

B

Barber-Zucker, Shiran, Hall, Jenny, Mangapuram, Sivasubramanyan Venkata, Kass, Itamar, Kolusheva, Sofiya, MacMillan, Fraser ORCID: https://orcid.org/0000-0002-2410-4790, Zarivach, Raz and Henn, Arnon (2019) Metal binding to the dynamic cytoplasmic domain of the cation diffusion facilitator (CDF) protein MamM induces a 'locked-in' configuration. FEBS Journal, 286 (11). pp. 2193-2215. ISSN 1742-464X

Bennett, Elliot, Lawrence, Elliot, Blagg, Robin, Mullen, Anna, Macmillan, Fraser ORCID: https://orcid.org/0000-0002-2410-4790, Ehlers, Andreas, Scott, Daniel, Sapsford, Joshua, Ashley, Andrew, Wildgoose, Gregory and Slootweg, Chris (2019) A new mode of chemical reactivity for metal-free hydrogen activation by Lewis acidic boranes. Angewandte Chemie-International Edition, 58 (25). pp. 8362-8366. ISSN 1433-7851

Bennett, Sophie, Soriano-Laguna, Manuel, Bradley, Justin, Svistunenko, Dimitri A., Richardson, David ORCID: https://orcid.org/0000-0002-6847-1832, Gates, Andrew ORCID: https://orcid.org/0000-0002-4594-5038 and Le Brun, Nicolas ORCID: https://orcid.org/0000-0001-9780-4061 (2019) NosL is a dedicated copper chaperone for assembly of the Cuz center of nitrous oxide reductase. Chemical Science, 10 (19). pp. 4985-4993. ISSN 2041-6520

Bradley, Justin M., Svistunenko, Dimitri A., Pullin, Jacob, Hill, Natalie, Stuart, Rhona K., Palenik, Brian, Wilson, Michael T., Hemmings, Andrew M. ORCID: https://orcid.org/0000-0003-3053-3134, Moore, Geoffrey R. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2019) Reaction of O2 with a di-iron protein generates a mixed valent Fe2+/Fe3+ center and peroxide. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 116 (6). pp. 2058-2067. ISSN 1091-6490

Bridge, Thomas, Shaikh, Saher A., Thomas, Paul, Botta, Joaquin, McCormick, Peter J. and Sachdeva, Amit (2019) Site‐specific encoding of photoactivity in antibodies enables light‐mediated antibody‐antigen binding on live cells. Angewandte Chemie, 58 (50). pp. 17986-17993. ISSN 0044-8249

C

Child, Simon, Raychev, Radoslav, Moss, Nathan, Howchen, Benjamin, Horton, Peter N., Prior, Christopher, Oganesyan, Vasily ORCID: https://orcid.org/0000-0002-8738-1146 and Fielden, John ORCID: https://orcid.org/0000-0001-5963-7792 (2019) Cobalt-based molecular electrocatalysis of nitrile reduction: evolving sustainability beyond hydrogen. Dalton Transactions, 48 (26). pp. 9576-9580. ISSN 1477-9226

Crack, Jason, Stewart, Melissa and Le Brun, Nicolas ORCID: https://orcid.org/0000-0001-9780-4061 (2019) Generation of 34S-substituted protein-bound [4Fe-4S] clusters using 34S-L-cysteine. Biology Methods and Protocols, 4 (1). ISSN 2396-8923

Crack, Jason C. and Le Brun, Nicolas ORCID: https://orcid.org/0000-0001-9780-4061 (2019) Mass spectrometric identification of [4Fe-4S](NO)x intermediates of nitric oxide sensing by regulatory iron-sulfur cluster proteins. Chemistry - A European Journal, 25 (14). pp. 3675-3684. ISSN 0947-6539

H

Hodgson, Hannah, De La Peña, Ricardo, Stephenson, Michael J. ORCID: https://orcid.org/0000-0002-2594-1806, Thimmappa, Ramesh, Vincent, Jason L., Sattely, Elizabeth S. and Osbourn, Anne (2019) Identification of key enzymes responsible for protolimonoid biosynthesis in plants: Opening the door to azadirachtin production. Proceedings of the National Academy of Sciences, 116 (34). pp. 17096-17104. ISSN 0027-8424

J

Jenner, Leon P., Kurth, Julia M., van Helmont, Sebastian, Sokol, Katarzyna P., Reisner, Erwin, Dahl, Christiane, Bradley, Justin M., Butt, Julea N. ORCID: https://orcid.org/0000-0002-9624-5226 and Cheesman, Myles (2019) Heme ligation and redox chemistry in two bacterial thiosulfate dehydrogenase (TsdA) enzyme. Journal of Biological Chemistry, 294 (47). pp. 18002-18014. ISSN 0021-9258

Jones, Hannah B. L., Crean, Rory M, Mullen, Anna, Kendrick, Emanuele, Bull, Steven D., Wells, Stephen A., Carbery, David Ross, Macmillan, Fraser ORCID: https://orcid.org/0000-0002-2410-4790, Van Der Kamp, Marc W. and Pudney, Christopher Roland (2019) Exposing the interplay between enzyme turnover, protein dynamics and the membrane environment in monoamine oxidase B. Biochemistry, 58 (18). 2362–2372. ISSN 0006-2960

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Kay, Kristine L., Hamilton, Chris J. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2019) Mass spectrometric studies of Cu(I)-binding to the N-terminal domains of B. subtilis CopA and influence of bacillithiol. Journal of Inorganic Biochemistry, 190. pp. 24-30. ISSN 0162-0134

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Leveau, Aymeric, Reed, James, Qiao, Xue, Stephenson, Michael J. ORCID: https://orcid.org/0000-0002-2594-1806, Mugford, Sam T., Melton, Rachel E., Rant, Jenni C., Vickerstaff, Robert, Langdon, Tim and Osbourn, Anne (2019) Towards take-all control: a C-21β oxidase required for acylation of triterpene defence compounds in oat. New Phytologist, 221 (3). pp. 1544-1555. ISSN 0028-646X

Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X and McGowan, Patrick C. (2019) Organometallic iridium arene compounds: The effects of C-donor ligands on anticancer activity. Chemistry Letters, 48 (8). pp. 916-924. ISSN 0366-7022

Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X, Zegke, Markus, Henderson, Imogen R., Pask, Christopher M., Shepherd, Helena J. and McGowan, Patrick C. (2019) β-Ketoiminato iridium(III) organometallic complexes: Selective cytotoxicity towards colorectal cancer cells HCT116 p53 -/-. Chemistry - A European Journal, 25 (2). pp. 495-500. ISSN 0947-6539

M

Madzivire, Cecilia R., Carames-Mendez, Pablo, Pask, Christopher M., Phillips, Roger M., Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X and McGowan, Patrick C. (2019) Anticancer, antifungal and antibacterial potential of bis(beta-ketoiminato) ruthenium(II) carbonyl complexes. Inorganica Chimica Acta, 498. ISSN 0020-1693

O

Orme, Anastasia, Louveau, Thomas, Stephenson, Michael J. ORCID: https://orcid.org/0000-0002-2594-1806, Appelhagen, Ingo, Melton, Rachel, Cheema, Jitender, Li, Yan, Zhao, Qiang, Zhang, Lei, Fan, Danlin, Tian, Qilin, Vickerstaff, Robert J., Langdon, Tim, Han, Bin and Osbourn, Anne (2019) A noncanonical vacuolar sugar transferase required for biosynthesis of antimicrobial defense compounds in oat. Proceedings of the National Academy of Sciences of the United States of America, 116 (52). pp. 27105-27114. ISSN 0027-8424

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Pellicer Martinez, Maria Teresa, Crack, Jason, Stewart, Melissa, Bradley, Justin, Svistunenko, Dimitri A., Johnston, Andrew, Cheesman, Myles, Todd, Jonathan and Le Brun, Nick ORCID: https://orcid.org/0000-0001-9780-4061 (2019) Mechanisms of iron- and O2-sensing by the [4Fe-4S] cluster of the global iron regulator RirA. eLife, 8. ISSN 2050-084X

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Ross, Matthew O, MacMillan, Fraser ORCID: https://orcid.org/0000-0002-2410-4790, Wang, Jingzhou, Nisthal, Alex, Lawton, Thomas J, Olafson, Barry D, Mayo, Stephen L, Rosenzweig, Amy C and Hoffman, Brian M (2019) Particulate methane monooxygenase contains only mononuclear copper centers. Science, 364 (6440). pp. 566-570. ISSN 0036-8075

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Stephenson, M.J. ORCID: https://orcid.org/0000-0002-2594-1806, Field, R.A. ORCID: https://orcid.org/0000-0001-8574-0275 and Osbourn, A. (2019) The protosteryl and dammarenyl cation dichotomy in polycyclic triterpene biosynthesis revisited: Has this 'rule' finally been broken? Natural Product Reports, 36. pp. 1044-1052. ISSN 0265-0568

Stikane, Anna, Hwang, Ee Taek, Ainsworth, Emma, Piper, Samuel, Critchley, Kevin, Butt, Julea ORCID: https://orcid.org/0000-0002-9624-5226, Reisner, Erwin and Jeuken, Lars J. C. (2019) Towards compartmentalized photocatalysis: Multiheme proteins as transmembrane molecular electron conduits. Faraday Discussions, 215. pp. 26-38. ISSN 1364-5498

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Volbeda, Anne, Pellicer Martinez, Ma Teresa, Crack, Jason C., Amara, Patricia, Gigarel, Océane, Munnoch, John T., Hutchings, Matthew I., Darnault, Claudine, Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 and Fontecilla-Camps, Juan C. (2019) Crystal structure of the transcription regulator RsrR reveals a [2Fe-2S] cluster coordinated by Cys, Glu and His residues. Journal of the American Chemical Society, 141 (6). 2367–2375. ISSN 0002-7863

van Wonderen, Jessica H., Hall, Christopher R., Jiang, Xiuyun, Adamczyk, Katrin, Carof, Antoine, Heisler, Ismael, Piper, Samuel E. H., Clarke, Thomas A. ORCID: https://orcid.org/0000-0002-6234-1914, Watmough, Nicholas J., Sazanovich, Igor V., Towrie, Michael, Meech, Stephen R. ORCID: https://orcid.org/0000-0001-5561-2782, Blumberger, Jochen and Butt, Julea N. ORCID: https://orcid.org/0000-0002-9624-5226 (2019) Ultrafast light-driven electron transfer in a Ru(II)tris(bipyridine)-labelled multiheme cytochrome. Journal of the American Chemical Society, 141 (38). pp. 15190-15200. ISSN 0002-7863

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Wahl, Lloyd C., Watt, Jessica E., Yim, Hiu Tung, De Bourcier, Danielle, Tolchard, James, Soond, Surinder, Blumenschein, Tharin ORCID: https://orcid.org/0000-0002-4932-5178 and Chantry, Andrew (2019) Smad7 binds differently to individual and tandem WW3 and WW4 domains of WWP2 ubiquitin ligase isoforms. International Journal of Molecular Sciences, 20 (19). ISSN 1661-6596

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Zegke, Markus, Spencer, Hannah L. M. and Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X (2019) Fast, facile and solvent-free dry-melt synthesis of oxovanadium(IV) complexes: Simple design with high potency towards cancerous cells. Chemistry - A European Journal, 25 (53). pp. 12275-12280. ISSN 0947-6539

Zegke, Markus, Zhang, Xiaobin, Pidchenko, Ivan, Hlina, Johann A., Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X, Purkis, Jamie, Nichol, Gary S., Magnani, Nicola, Schreckenbach, Georg, Vitova, Tonya, Love, Jason B. and Arnold, Polly L. (2019) Differential uranyl(v) oxo-group bonding between the uranium and metal cations from groups 1, 2, 4, and 12; a high energy resolution X-ray absorption, computational, and synthetic study. Chemical Science, 10. pp. 9740-9751. ISSN 2041-6520