Items where Research Group is "Chemical Biology and Medicinal Chemistry (former - to 2021)

B

Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406 and Barrow, Russell Allan (2013) Stereochemical assignment of the fungal metabolites Pestalotiopsones D and E through enantiopure synthesis. Journal of Natural Products, 76 (11). pp. 2054-2059. ISSN 0163-3864

Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, Castillo Martinez, Edwin and Barrow, Russell Allan (2013) First syntheses of the biologically active fungal metabolites pestalotiopsones A, B, C and F. Organic & Biomolecular Chemistry, 11 (7). pp. 1109-1115. ISSN 1477-0520

Brissonnet, Yoan, Ortiz Mellet, Carmen, Morandat, Sandrine, Garcia Moreno, M. Isabel, Deniaud, David, Matthews, Susan ORCID: https://orcid.org/0000-0001-8821-0851, Vidal, Sebastien, Sestak, Sergej, El Kirat, Karim and Gouin, Sebastien G. (2013) Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and mannosidases. Journal of the American Chemical Society, 135 (49). pp. 18427-18435. ISSN 0002-7863

C

Chi, Bui Khanh, Roberts, Alexandra A., Huyen, Tran Thi Thanh, Bäsell, Katrin, Becher, Dörte, Albrecht, Dirk, Hamilton, Chris J. and Antelmann, Haike (2013) S-Bacillithiolation protects conserved and essential proteins against hypochlorite stress in Firmicutes bacteria. Antioxidants & Redox Signaling, 18 (11). pp. 1273-1295. ISSN 1523-0864

D

Day, Henry A., Huguin, Camille and Waller, Zoe A. E. (2013) Silver cations fold i-motif at neutral pH. Chemical Communications, 49 (70). pp. 7696-7698. ISSN 1359-7345

F

Fang, Zhong, Roberts, Alexandra A., Weidman, Karissa, Sharma, Sunil C., Claiborne, Al, Hamilton, Christopher and Dos Santos, Patricia C. (2013) Cross functionalities of Bacillus deacetylases involved in bacillithial biosynthesis and bacillitiol-S-conjugate detoxification pathways. Biochemistry Journal, 454 (2). pp. 239-247.

G

Gaballa, A., Antelmann, H., Hamilton, C. J. and Helmann, J. D. (2013) Regulation of Bacillus subtilis bacillithiol biosynthesis operons by Spx. Microbiology, 159 (Pt_10). pp. 2025-2035. ISSN 1350-0872

I

Iqbal, Amjid, Chibli, Hicham and Hamilton, Christopher (2013) Stability of aminooxy glycosides to glycosidase catalysed hydrolysis. Carbohydrate Research, 377. pp. 1-3. ISSN 0008-6215

L

Lincheneau, Christophe, Quinlan, Eoin, Kitchen, Jonathan A., McCabe, Thomas, Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 and Gunnlaugsson, Thorfinnur (2013) Delayed lanthanide luminescent Tb(III) complexes formed from lower rim amide functionalised calix[4]arenes. Supramolecular Chemistry, 25 (12). pp. 869-880. ISSN 1061-0278

M

Marin, MJ ORCID: https://orcid.org/0000-0001-8021-5498, Rackham, Benjamin D., Round, Andrew N. ORCID: https://orcid.org/0000-0001-9026-0620, Howell, Lesley A., Russell, David A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2013) A rapid screen for molecules that form duplex to duplex crosslinks in DNA. Chemical Communications, 49 (80). p. 9113. ISSN 1359-7345

P

Pöther, Dierk-Christoph, Gierok, Philipp, Harms, Manuela, Mostertz, Jörg, Hochgräfe, Falko, Antelmann, Haike, Hamilton, Christopher, Borovok, Ilya, Lalk, Michael, Aharonowitz, Yair and Hecker, Michael (2013) Distribution and infection-related functions of bacillithiol in Staphylococcus aureus. International Journal of Medical Microbiology, 303 (3). pp. 114-123. ISSN 1438-4221

R

Rackham, Benjamin D., Howell, Lesley A., Round, Andrew N. ORCID: https://orcid.org/0000-0001-9026-0620 and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2013) Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy. Organic & Biomolecular Chemistry, 11 (48). pp. 8340-8347. ISSN 1477-0520

Rajkarnikar, Arishma, Strankman, Andrew, Duran, Shayla, Vargas, Derek, Roberts, Alexandra A., Barretto, Kathryn, Upton, Heather, Hamilton, Christopher J. and Rawat, Mamta (2013) Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus. Biochemical and Biophysical Research Communications, 436 (2). pp. 128-133. ISSN 0006-291X

Roberts, Alexandra A., Sharma, Sunil V., Strankman, Andrew W., Duran, Shayla R., Rawat, Mamta and Hamilton, Chris J. (2013) Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus. Biochemical Journal, 451 (1). pp. 69-79. ISSN 0264-6021

Robertson, James C., Hurley, Nate C., Tortorici, Marcello, Ciossani, Giuseppe, Borrello, Maria Teresa, Vellore, Nadeem A., Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Mattevi, Andrea and Baron, Riccardo (2013) Expanding the druggable space of the LSD1/CoREST epigenetic target: New potential binding regions for drug-like molecules, peptides, protein partners, and chromatin. PLoS Computational Biology, 9 (7). ISSN 1553-7358

S

Sharma, Sunil V., Arbach, Miriam, Roberts, Alexandra A., Macdonald, Colin J., Groom, Murree and Hamilton, Chris J. (2013) Biophysical features of bacillithiol, the glutathione surrogate of Bacillus subtilis and other firmicutes. ChemBioChem, 14 (16). pp. 2160-2168. ISSN 1439-4227

Sheldrake, Helen M., Travica, Sandra, Johansson, Inger, Loadman, Paul M., Sutherland, Mark, Elsalem, Lina, Illingworth, Nicola, Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven D., Mkrtchian, Souren, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Ingelman-Sundberg, Magnus, Patterson, Laurence H. and Pors, Klaus (2013) Re-engineering of the duocarmycin structural architecture enables bioprecursor development targeting CYP1A1 and CYP2W1 for biological activity. Journal of Medicinal Chemistry, 56 (15). pp. 6273-6277. ISSN 0022-2623

Sutherland, Mark, Gill, Jason H, Loadman, Paul M, Laye, Jonathan P, Sheldrake, Helen M, Illingworth, Nicola A, Alandas, Mohammed N, Cooper, Patricia A, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Pors, Klaus, Shnyder, Steve D and Patterson, Laurence H (2013) Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder. Molecular Cancer Therapeutics, 12 (1). pp. 27-37. ISSN 1538-8514

T

Tortorici, Marcello, Borrello, Maria Teresa, Tardugno, Maria, Chiarelli, Laurent R, Pilotto, Simona, Ciossani, Giuseppe, Vellore, Nadeem A, Bailey, Sarah G, Cowan, Jonathan, O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951, Crabb, Simon J, Packham, Graham, Mai, Antonello, Baron, Riccardo, Ganesan, A ORCID: https://orcid.org/0000-0003-4862-7999 and Mattevi, Andrea (2013) Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase. ACS Chemical Biology, 8 (8). pp. 1677-1682. ISSN 1554-8937

U

Ukhatskaya, E.V., Kurkov, S.V., Matthews, S.E. ORCID: https://orcid.org/0000-0001-8821-0851 and Loftsson, T. (2013) Encapsulation of drug molecules into Calix[n]arene Nanobaskets. Role of Aminocalix[n]arenes in biopharmaceutical field. Journal of Pharmaceutical Sciences, 102 (10). pp. 3485-3512. ISSN 0022-3549

Ukhatskaya, Elena V., Kurkov, Sergey V., Hjálmarsdóttir, Martha A., Karginov, Vladimir A., Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851, Rodik, Roman V., Kalchenko, Vitaly I. and Loftsson, Thorsteinn (2013) Cationic quaternized aminocalix[4]arenes: Cytotoxicity, haemolytic and antibacterial activities. International Journal of Pharmaceutics, 458 (1). pp. 25-30. ISSN 0378-5173

W

Wossa, Stewart W., Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406, Ma, Paul, Kevo, Oromo and Barrow, Russell A. (2013) Identification of boletopsin 11 and 12, antibiotics from the traditionally used fungus Boletopsis sp. Asian Journal of Organic Chemistry, 2 (7). pp. 565-567. ISSN 2193-5807