Items where Author is "Fountain, Samuel"

Article

Fortuny-Gomez, Anna and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2024) Pharmacological differences between human and mouse P2X4 receptor explored using old and new tools. Purinergic Signalling, 20 (6). pp. 659-667. ISSN 1573-9538

del Carmen Gonzalez-Montelongo, Maria, Meades, Jessica Lauren, Fortuny-Gomez, Anna and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2023) Neuropeptide Y: Direct vasoconstrictor and facilitatory effects on P2X1 receptor-dependent vasoconstriction in human small abdominal arteries. Vascular Pharmacology, 151. ISSN 1537-1891

Majeed, Yasser, Madani, Aisha Y., Altamimi, Ahmed I., Courjaret, Raphael, Vakayil, Muneera, Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Machaca, Khaled and Mazloum, Nayef A. (2023) STAT1- and NFAT-independent amplification of purinoceptor function integrates cellular senescence with interleukin-6 production in preadipocytes. British Journal of Pharmacology, 180 (5). pp. 609-627. ISSN 0007-1188

Day-Walsh, Priscilla, Keeble, Bryony, Pirabagar, Gothai, Fountain, Samuel ORCID: https://orcid.org/0000-0002-6028-0548 and Kroon, Paul (2022) Transcriptional and post-translational regulation of junctional adhesion molecule-B (JAM-B) in leukocytes under inflammatory stimuli. International Journal of Molecular Sciences, 23 (15). ISSN 1661-6596

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Nadzirin, Izzuddin Bin, Cominetti, Marco, Hickey, Harry, Cullum, Sean A., Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Schmid, Ralf and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2022) Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors. Molecular Pharmacology, 101 (1). pp. 33-44. ISSN 1521-0111

Nadzirin, Izzuddin Bin, Fortuny‐Gomez, Anna, Ngum, Neville, Richards, David, Ali, Seema, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2021) Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3‐kinase inhibition. British Journal of Pharmacology, 178 (24). pp. 4859-4872. ISSN 0007-1188

Gonzalez-Montelongo, Maria and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2021) Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses. Vascular Pharmacology, 136. ISSN 1537-1891

Illes, Peter, Müller, Christa E., Jacobson, Kenneth A., Grutter, Thomas, Nicke, Annette, Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Kennedy, Charles, Schmalzing, Günther, Jarvis, Michael F., Stojilkovic, Stanko S., King, Brian F. and Di Virgilio, Francesco (2021) Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. British Journal of Pharmacology, 178 (3). pp. 489-514. ISSN 0007-1188

Porter, Sarah, Minaisah, Rose Marie, Ahmed, Sultan, Ali, Seema, Norton, Rosemary, Zhang, Qiuping, Ferraro, Elisa, Molenaar, Chris, Holt, Mark, Cox, Susan, Fountain, Samuel ORCID: https://orcid.org/0000-0002-6028-0548, Shanahan, Catherine and Warren, Derek (2020) SUN1/2 are essential for RhoA/ROCK-regulated actomyosin activity in isolated vascular smooth muscle cells. Cells, 9 (1). ISSN 2073-4409

Layhadi, Janice A. and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2019) ATP-evoked intracellular Ca2+ responses in M-CSF differentiated human monocyte-derived macrophage are mediated by P2X4 and P2Y11 receptor activation. International Journal of Molecular Sciences, 20 (20). ISSN 1661-6596

Day, Priscilla, Burrows, Lisa, Richards, David and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2019) Inhibitors of diacylglycerol metabolism suppress CCR2 receptor signalling in human monocytes. British Journal of Pharmacology, 176 (15). pp. 2736-2749. ISSN 0007-1188

Richards, David, Gever, Joel R., Ford, Anthony P. and Fountain, Samuel ORCID: https://orcid.org/0000-0002-6028-0548 (2019) Action of MK‐7264 (Gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation. British Journal of Pharmacology, 176 (13). pp. 2279-2291. ISSN 0007-1188

Ali, Seema, Turner, Jeremy and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2018) P2Y2 and P2Y6 receptor activation elicits intracellular calcium responses in human adipose-derived mesenchymal stromal cells. Purinergic Signalling, 14 (4). 371–384. ISSN 1573-9538

Ali, Seema B., Turner, Jeremy J. O. and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2018) Constitutive P2Y2 receptor activity regulates basal lipolysis in human adipocytes. Journal of Cell Science, 131 (22). ISSN 0021-9533

Micklewright, J. J., Layhadi, J. A. and Fountain, S. J. ORCID: https://orcid.org/0000-0002-6028-0548 (2018) P2Y12 receptor modulation of ADP‐evoked intracellular Ca2+ signalling in THP-1 human monocytic cells. British Journal of Pharmacology, 175 (12). pp. 2483-2491. ISSN 0007-1188

Layhadi, Janice A., Turner, Jeremy, Crossman, David and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2018) ATP evokes Ca2+ responses and CXCL5 secretion via P2X4 receptor activation in human monocyte-derived macrophages. Journal of Immunology, 200 (3). pp. 1159-1168. ISSN 0022-1767

Layhadi, Janice and Fountain, Samuel ORCID: https://orcid.org/0000-0002-6028-0548 (2017) P2X4 receptor-dependent Ca2+ influx in model human monocytes and macrophages. International Journal of Molecular Sciences, 18 (11). ISSN 1661-6596

Layhadi, Janice A. and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2017) Influence of ER leak on resting cytoplasmic Ca2+ and receptormediated Ca2+ signalling in human macrophage. Biochemical and Biophysical Research Communications, 487 (3). 633–639. ISSN 0006-291X

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Layhadi, Janice A., Bibic, Lucka, Dhuna, Kshitija and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2017) P2X4 receptor function in the nervous system and current breakthroughs in pharmacology. Frontiers in Pharmacology, 8. ISSN 1663-9812

Fountain, Samuel ORCID: https://orcid.org/0000-0002-6028-0548 and Sivaramakrishnan, Venketesh (2015) Evidence for extracellular ATP as a stress signal in a single-celled organism. Eukaryotic Cell, 14 (8). pp. 775-782. ISSN 1535-9786

Campwala, H., Sexton, D. W., Crossman, D. C. and Fountain, S. J. ORCID: https://orcid.org/0000-0002-6028-0548 (2014) P2Y6 receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells. Journal of Cell Science, 127 (22). pp. 4964-4973. ISSN 0021-9533

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2013) Primitive ATP-activated P2X receptors: discovery, function and pharmacology. Frontiers in Cellular Neuroscience, 7. ISSN 1662-5102

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2013) Fourth (2012) UK purine club annual symposium report. Purinergic Signalling, 9 (4). ISSN 1573-9538

Campwala, Hinnah and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2013) Constitutive and agonist stimulated ATP secretion in leukocytes. Communicative and Integrative Biology, 6 (3). e23631. ISSN 1942-0889

Sivaramakrishnan, Venketesh and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2013) Intracellular P2X receptors as novel calcium release channels and modulators of osmoregulation in Dictyostelium: A comparison of two common laboratory strains. Channels, 7 (1). pp. 43-46. ISSN 1933-6950

Sivaramakrishnan, V., Bidula, S. ORCID: https://orcid.org/0000-0002-3790-7138, Campwala, H., Katikaneni, D. and Fountain, S. J. ORCID: https://orcid.org/0000-0002-6028-0548 (2012) Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes. Journal of Cell Science, 125 (19). pp. 4567-4575. ISSN 0021-9533

Sivaramakrishnan, Venketesh and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2012) A mechanism of intracellular P2X receptor activation. Journal of Biological Chemistry, 287 (34). pp. 28315-28326. ISSN 0021-9258

Li, Jing and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2012) Fluvastatin suppresses native and recombinant human P2X4 receptor function. Purinergic Signalling, 8 (2). pp. 311-316. ISSN 1573-9538

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2010) Neurotransmitter receptor homologues of Dictyostelium discoideum. Journal of Molecular Neuroscience, 41 (2). pp. 263-266. ISSN 1559-1166

Cheong, Alex, Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 and Beech, David J. (2009) Quantitative RT-PCR methods for investigation of low copy potassium channel gene expression in native murine arteries. Potassium Channels, 491 (I). pp. 19-33.

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 and Burnstock, Geoffrey (2009) An evolutionary history of P2X receptor. Purinergic Signalling, 5 (3). pp. 269-272.

Young, Mark T., Fisher, James A., Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Ford, Robert C., North, R. Alan and Khakh, Baljit S. (2008) Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopy. The Journal of Biological Chemistry, 283 (38). pp. 26241-26251. ISSN 1083-351X

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Cao, Lishuang, Young, Mark T. and North, R. Alan (2008) Permeation properties of a P2X receptor in the green algae Ostreococcus tauri. The Journal of Biological Chemistry, 283. pp. 15122-15126. ISSN 1083-351X

Cao, Lishuang, Young, Mark T., Broomhead, Helen E., Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 and North, Alan R. (2007) Thr339-to-serine substitution in Rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308. The Journal of Neuroscience, 27 (47). pp. 12916-12923. ISSN 1529-2401

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Cheong, Alex, Li, Jing, Dondas, Naciye Y., Zeng, Fanning, Wood, Ian C. and Beech, David J. (2007) Kv1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress. AJP - Heart and Circulatory Physiology, 293 (5). pp. 2719-2725.

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Parkinson, Katie, Young, Mark T., Cao, Lishuang, Thompson, Christopher R. L. and North, Alan R. (2007) An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum. Nature, 448. pp. 200-203.

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 and North, Alan R. (2006) A C-terminal lysine that controls human P2X4 receptor desensitization. The Journal of Biological Chemistry, 281. pp. 15044-15049. ISSN 1083-351X

Zeng, Fanning, Xu, Shang-Zhong, Jackson, Philippa K., McHugh, Damian, Kumar, Bhaskar, Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 and Beech, David R. (2004) Human TRPC5 channel activated by a multiplicity of signals in a single cell. The Journal of Physiology, 559 (3). pp. 739-750. ISSN 1469-7793

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548, Cheong, A., Flemming, R., Mair, L., Sivaprasadarao, A. and Beech, D. J. (2004) Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle. The Journal of Physiology, 556 (1). pp. 29-42. ISSN 1469-7793

Book Section

Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2023) Purinergic neurotransmission and nucleotide receptors. In: Primer on the Autonomic Nervous System, Fourth Edition. Elsevier, pp. 93-97. ISBN 978-0-323-85492-4