Correlation between second trimester weight gain and perinatal outcomes in dichorionic twin pregnancies: The LoTiS cohort study

Wen, Li, Liu, Xiyao, Wang, Lan, Zheng, Yangxi, Li, Jie, Tong, Chao, Qi, Hongbo, Saffery, Richard and Baker, Philip ORCID: https://orcid.org/0000-0002-4592-6427 (2019) Correlation between second trimester weight gain and perinatal outcomes in dichorionic twin pregnancies: The LoTiS cohort study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 233. pp. 64-69. ISSN 0301-2115

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Abstract

Purpose: To investigate how second trimester gestational weight gain relates to perinatal outcomes in twin pregnancies of the LoTiS cohort in Chongqing, China. Methods: A cohort study was conducted among women with dichorionic twin pregnancies; pregnancies that culminated in delivery at ≥20 gestational weeks were included in the analysis (n = 177). Data were collected through the Longitudinal Twin Study (LoTiS). The second trimester was divided into two periods: 12–20 and 21–28 gestational weeks. Correlations between maternal weight gain and perinatal outcomes were estimated using linear or logistic regression models; the crude OR and adjusted OR were calculated. Results: The average total gestational weight gain for the whole pregnancy was 17.71 ± 4.98 kg and average gestational weight gains during 12–20 gestational weeks and 20–28 gestational weeks were 5.11 ± 1.81 kg and 5.84 ± 2.05 kg, respectively. Insufficient gestational weight gain was associated with higher risk of preterm birth (OR = 0.92, 95% CI 0.86-0.99) and spontaneous preterm birth (OR = 0.89, 95% CI 0.82–0.97). Reduced gestational weight gain during 12–20 gestational weeks was associated with higher risk of small for gestational age. Additionally, the mean birth weight of a twin pair increased by 45.78 g or 13.03 g when gestational weight gain during 12–20 weeks or total gestational weight gain increased by 1 kg. Conclusion: Maternal weight gain in the early second trimester was correlated with birth weight in dichorionic twins.

Item Type: Article
Additional Information: Publisher Copyright: © 2018 Elsevier B.V.
Uncontrolled Keywords: gestational weight gain,perinatal outcomes,twin pregnancies,reproductive medicine,obstetrics and gynaecology ,/dk/atira/pure/subjectarea/asjc/2700/2743
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 26 Jun 2025 16:30
Last Modified: 18 Jun 2026 20:39
URI: https://ueaeprints.uea.ac.uk/id/eprint/99744
DOI: 10.1016/j.ejogrb.2018.12.014

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