Correlation between second trimester weight gain and perinatal outcomes in dichorionic twin pregnancies:The LoTiS cohort study

Wen, Li, Liu, Xiyao, Wang, Lan, Zheng, Yangxi, Li, Jie, Tong, Chao, Qi, Hongbo, Saffery, Richard and Baker, Philip (2019) Correlation between second trimester weight gain and perinatal outcomes in dichorionic twin pregnancies:The LoTiS cohort study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 233. pp. 64-69. ISSN 0301-2115

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Abstract

Purpose: To investigate how second trimester gestational weight gain relates to perinatal outcomes in twin pregnancies of the LoTiS cohort in Chongqing, China. Methods: A cohort study was conducted among women with dichorionic twin pregnancies; pregnancies that culminated in delivery at ≥20 gestational weeks were included in the analysis (n = 177). Data were collected through the Longitudinal Twin Study (LoTiS). The second trimester was divided into two periods: 12–20 and 21–28 gestational weeks. Correlations between maternal weight gain and perinatal outcomes were estimated using linear or logistic regression models; the crude OR and adjusted OR were calculated. Results: The average total gestational weight gain for the whole pregnancy was 17.71 ± 4.98 kg and average gestational weight gains during 12–20 gestational weeks and 20–28 gestational weeks were 5.11 ± 1.81 kg and 5.84 ± 2.05 kg, respectively. Insufficient gestational weight gain was associated with higher risk of preterm birth (OR = 0.92, 95% CI 0.86-0.99) and spontaneous preterm birth (OR = 0.89, 95% CI 0.82–0.97). Reduced gestational weight gain during 12–20 gestational weeks was associated with higher risk of small for gestational age. Additionally, the mean birth weight of a twin pair increased by 45.78 g or 13.03 g when gestational weight gain during 12–20 weeks or total gestational weight gain increased by 1 kg. Conclusion: Maternal weight gain in the early second trimester was correlated with birth weight in dichorionic twins.

Item Type: Article
Additional Information: Publisher Copyright: © 2018 Elsevier B.V.
Uncontrolled Keywords: gestational weight gain,perinatal outcomes,twin pregnancies,reproductive medicine,obstetrics and gynaecology ,/dk/atira/pure/subjectarea/asjc/2700/2743
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 26 Jun 2025 16:30
Last Modified: 26 Jun 2025 16:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/99744
DOI: 10.1016/j.ejogrb.2018.12.014

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