What Information exists about the disease and health systems burdens of lesser studied enteric viral infections in north west Europe? A rapid systematic mapping review

Brainard, Julii, Wang-Steverding, Xia and Swindells, Isabel Catalina (2025) What Information exists about the disease and health systems burdens of lesser studied enteric viral infections in north west Europe? A rapid systematic mapping review.

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Abstract

Background: Availability of multiplex PCR methods means that less studied viruses are often linked to acute gastrointestinal infection. Among the virus genera increasingly linked to illness and health care usage are astroviruses, sapoviruses, enteric adenoviruses and parechoviruses. Methods: A systematic mapping review was undertaken to evaluate availability of published evidence that might be used to describe the disease burden or health care system usage associated with infection status with the target viruses among north west European populations. Availability of information was tabulated with respect to which viruses were tested, specific symptoms, sequelae and indicators of health service usage. Results: At least 49 studies were available that described outcomes related to each of the target viruses. The most commonly documented symptom was presence/absence of diarrhoea. Metrics such as hospitalisation rates were available in a minority of studies, and no data were published about disability-adjusted-life-years, quality-of-life or life expectancy in relation to infection status. Conclusions: It is feasible to estimate typical rates of hospitalisation or length of stay with infection by astroviruses, sapoviruses, enteric adenoviruses or parechoviruses.

Item Type: Article
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
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Depositing User: LivePure Connector
Date Deposited: 18 Jun 2025 11:30
Last Modified: 23 Jun 2025 00:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/99621
DOI: 10.1101/2025.06.09.25329265

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