The prevalence and associated factors of prenatal depression and anxiety in twin pregnancy: A cross-sectional study in Chongqing, China

Zhou, Ying, Huang, Jingui, Baker, Philip N., Liao, Bizhen and Yu, Xinyang (2022) The prevalence and associated factors of prenatal depression and anxiety in twin pregnancy: A cross-sectional study in Chongqing, China. BMC Pregnancy and Childbirth, 22. ISSN 1471-2393

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Abstract

Background: Pregnant women expecting twins are more likely to experience stress, which can lead to anxiety and depression. Our aim was to investigate the prevalence of prenatal anxiety and depressive symptoms in women with twin pregnancies and the associated factors. Methods: In a cross-sectional survey, 210 women with twin pregnancies who satisfied the inclusion and exclusion criteria in two tertiary centers in Southwestern China were asked to complete a basic information form, the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS). To compare statistics with normal distribution in distinct characteristic groups, a paired t-test, and one-way ANOVA were utilized. Binary logistic step regression was used to analyze the associated factors of antenatal anxiety and depressive symptoms. Results: The 210 women with twin pregnancies (age = 30.8 ± 4.2 years) were between 7 and 37 gestational weeks (29.2 ± 1.2 weeks), were typically well-educated (72.4% had a post-high-school degree), and reasonably affluent (88.1% were above the low-income cutoff). Among them, 34.8% had symptoms associated with clinical levels of anxiety, and 37.1% had symptoms indicating possible depression. The prevalence of co-morbid anxiety and depressive symptoms was 24.3%. Binary stepwise logistic regression analysis showed that previous health status and sleep disturbance during pregnancy were the associated factors of anxiety symptoms in women with twin pregnancies (P < 0.05), whereas age, previous health status, negative life events, and physical activity during pregnancy were the associated factors of depressive symptoms in women with twin pregnancies (P < 0.05). Conclusion: About one-third of women with twin pregnancies had symptoms of anxiety or depression; these were most strongly predicted by some modifiable factors, suggesting that early preventive mind-body interventions may be a promising strategy to protect against mental health issues for women with twin pregnancies.

Item Type: Article
Additional Information: Availability of data and materials: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Funding information: This research was supported by grants from the Discipline Innovation Foundation in Discipline Cultivation Project of the First Affiliated Hospital of Chongqing Medical University (XKTS121); the funders had no role in the design of the study, the collection, analysis, and interpretation of data, or in writing the manuscript.
Uncontrolled Keywords: anxiety,depression,maternal mental health,prevalence,twin pregnancy,obstetrics and gynaecology ,/dk/atira/pure/subjectarea/asjc/2700/2729
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 08 May 2025 11:31
Last Modified: 08 May 2025 11:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/99219
DOI: 10.1186/s12884-022-05203-y

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