Porocarcinoma: A review

Joshy, Jilse, Mistry, Khaylen, Levell, Nick J., Bodegraven, Birgitta, Vernon, Sally, Rajan, Neil, Craig, Paul and Venables, Zoe Claire (2022) Porocarcinoma: A review. Clinical and Experimental Dermatology, 47 (6). pp. 1030-1035. ISSN 0307-6938

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Abstract

From the first report in 1969 to the present day, diagnosis of eccrine porocarcinoma, also known simply as porocarcinoma (PC), remains a challenge. This review presents a concise update of the history, pathogenesis, epidemiology, diagnosis, management and prognosis of this rare sweat gland neoplasm. PC differentiates towards the intraepidermal spiral ducts in the eccrine gland, is more common in people aged > 60 years and often affects the head, neck and legs. PC presents as a dome-shaped papule, plaque or nodule growing over weeks to months. The exact incidence of PC is unknown but appears to be rising. Diagnosis is difficult because of variable presentations and similar clinical and histological features to cutaneous squamous cell carcinoma. Management involves removal of the tumour, usually using wide local excision or Mohs micrographic surgery. Prognosis is poor, with PC recurring after surgery in 35% of cases. Given the lack of standardized protocols and risk profiles, further studies would help improve the understanding of PC.

Item Type: Article
Additional Information: Publisher Copyright: © 2022 British Association of Dermatologists.
Uncontrolled Keywords: dermatology ,/dk/atira/pure/subjectarea/asjc/2700/2708
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Population Health
Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
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Depositing User: LivePure Connector
Date Deposited: 31 Mar 2025 15:30
Last Modified: 03 Apr 2025 09:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/98914
DOI: 10.1111/ced.15126

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