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ToolsJoshy, Jilse, Mistry, Khaylen, Levell, Nick J., Bodegraven, Birgitta, Vernon, Sally, Rajan, Neil, Craig, Paul and Venables, Zoe Claire (2022) Porocarcinoma: A review. Clinical and Experimental Dermatology, 47 (6). pp. 1030-1035. ISSN 0307-6938
Full text not available from this repository. (Request a copy)Abstract
From the first report in 1969 to the present day, diagnosis of eccrine porocarcinoma, also known simply as porocarcinoma (PC), remains a challenge. This review presents a concise update of the history, pathogenesis, epidemiology, diagnosis, management and prognosis of this rare sweat gland neoplasm. PC differentiates towards the intraepidermal spiral ducts in the eccrine gland, is more common in people aged > 60 years and often affects the head, neck and legs. PC presents as a dome-shaped papule, plaque or nodule growing over weeks to months. The exact incidence of PC is unknown but appears to be rising. Diagnosis is difficult because of variable presentations and similar clinical and histological features to cutaneous squamous cell carcinoma. Management involves removal of the tumour, usually using wide local excision or Mohs micrographic surgery. Prognosis is poor, with PC recurring after surgery in 35% of cases. Given the lack of standardized protocols and risk profiles, further studies would help improve the understanding of PC.
| Item Type: | Article |
|---|---|
| Additional Information: | Publisher Copyright: © 2022 British Association of Dermatologists. |
| Uncontrolled Keywords: | dermatology ,/dk/atira/pure/subjectarea/asjc/2700/2708 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 31 Mar 2025 15:30 |
| Last Modified: | 06 Apr 2025 06:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/98914 |
| DOI: | 10.1111/ced.15126 |
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