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ToolsNatarajan, Rajkumar, Corballis, Natasha, Merinopoulos, Ioannis, Vassiliou, Vassilios S. and Eccleshall, Simon C. (2024) Coronary Dissection – Back to the Future – Finding Good in the Bad! Heart International, 18 (2). pp. 14-23. ISSN 1826-1868
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Abstract
It has been recognized for decades that dissections occur as a mechanism of balloon angioplasty. A successful angioplasty result contains some degree of intimal splitting and disruption, which usually heals well. Nonetheless, some dissections are extensive, leading to serious ischaemic complications. The concept of therapeutic coronary dissection started evolving in the 1970s and seems to be a favourable mechanism for drug delivery in the current era of drug-coated balloons. This article will primarily focus on studies undertaken to understand the mechanism of balloon angioplasty and the morphological changes in the plaque post-balloon angioplasty. In the early days of balloon angioplasty, there was an enormous interest in dissections, mainly to prevent acute vessel closure events and to address the importance of their occurrence in relation to vessel restenosis. We will review the historical background, studies defining the clinical, angiographic and morphological patterns of the dissection spectrum and various currently evolving management strategies.
| Item Type: | Article |
|---|---|
| Additional Information: | Publisher Copyright: © 2024, Touch Medical Media. All rights reserved. |
| Uncontrolled Keywords: | coronary dissections,coronary injury,dissection classification,dissection during drug-coated balloon (dcb) angioplasty,dissections and their management,dissections on oct,cardiology and cardiovascular medicine ,/dk/atira/pure/subjectarea/asjc/2700/2705 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 17 Mar 2025 14:30 |
| Last Modified: | 28 Mar 2025 13:14 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/98764 |
| DOI: | 10.17925/HI.2024.18.2.5 |
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