A history of polymyalgia rheumatica: A narrative review

Shah, Shirley, Rao, Sinchna, Mackie, Sarah L. and Mukhtyar, Chetan B. (2025) A history of polymyalgia rheumatica: A narrative review. Rheumatology, 64 (2). pp. 470-476. ISSN 1462-0324

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Abstract

Polymyalgia rheumatica (PMR) is characterized by stiffness and pain in the shoulders, hips and neck and presents most commonly in the eighth decade. It can coexist with giant cell arteritis and the two diseases may share some pathophysiological mechanisms. This narrative review considers present-day ideas about PMR in a historical context, from the first names and descriptions of this disease entity, via successive generations of classification criteria sets, and finally to implications for clinical diagnosis. The characteristic distribution of musculoskeletal inflammation in PMR and its relationship to vasculitic and synovitic diseases have framed the way that PMR is described, classified, diagnosed and treated. A response to glucocorticoids is not specific to PMR and so it is important for rheumatologists to support general practitioners in making a definite diagnosis. Multi-stakeholder collaboration will improve current pathways for fast, accurate diagnosis and safe and effective treatment.

Item Type: Article
Additional Information: Publisher Copyright: © 2024 The Author(s). Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.
Uncontrolled Keywords: attitude of health personnel,classification criteria,giant cell arteritis,history of medicine,polymyalgia rheumatica,rheumatology,pharmacology (medical) ,/dk/atira/pure/subjectarea/asjc/2700/2745
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 07 Mar 2025 18:30
Last Modified: 12 Mar 2025 09:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/98721
DOI: 10.1093/rheumatology/keae569

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