Tools
ToolsSedaghat, Ahmad R., Cotter, Ryan A., Alobid, Isam, Alsaleh, Saad, Anselmo-Lima, Wilma Terezinha, Bernal-Sprekelsen, Manuel, Chandra, Rakesh K., Constantinidis, Jannis, Fokkens, Wytske J., Franzese, Christine, Gray, Stacey T., Halderman, Ashleigh A., Holbrook, Eric H., Hopkins, Claire, Hwang, Peter H., Kuan, Edward C., Landis, Basile N., Lund, Valerie J., McCoul, Edward D., Niederberger-Leppin, Verena, O'Brien, Erin K., Philpott, Carl M., Pletcher, Steven D., Pynnonen, Melissa A., Reitsma, Sietze, Rimmer, Joanne, Toppila-Salmi, Sanna, Wang, Eric W., Wang, Marilene B., Wise, Sarah K., Woodworth, Bradford A., Yao, William C. and Phillips, Katie M. (2025) Nasal endoscopy score thresholds to trigger consideration of chronic rhinosinusitis treatment escalation and implications for disease control. Rhinology, 63 (1). pp. 54-62. ISSN 0300-0729
Preview |
PDF (manuscript CLEAN)
- Accepted Version
Download (392kB) | Preview |
Abstract
Background: In the absence of direct evidence supporting how to use nasal endoscopy findings to judge chronic rhinosinusitis (CRS) disease control, experts' practice patterns could provide guidance. Methodology: Participants consisted of a diverse group of twenty-nine rhinologists. Participants were presented with every possible combination of bilateral nasal endoscopy findings represented by the modified Lund-Kennedy (MLK; range: 0–12) endoscopic scoring system and Nasal Polyp Score (NPS; range: 0–8). Reflecting the practical consequence of CRS disease control assessment, participants were asked whether they would consider CRS treatment escalation based on each scenario in the absence of any CRS symptoms, and how strongly they considered escalating therapy. The same scenarios were then presented in the context of 1 burdensome CRS symptom and participants again were asked whether they would consider treatment escalation. Results: The median threshold total MLK score for considering treatment escalation was ≥4 and 75.9% of participants’ MLK thresholds were within 1 point of 4. The median threshold total NPS for considering treatment escalation was ≥3 and 62.5% of participants’ NPS thresholds were within 1 point of 3. Endoscopy score thresholds decreased in the presence of 1 burdensome symptom and generally increased when requiring stronger affirmation for considering CRS treatment escalation. Conclusion: Reflecting the practice patterns of a diverse group of rhinologists, MLK score ≥4 or NPS ≥3 may serve as thresholds for considering CRS treatment escalation. Alternatively, MLK score <4 or NPS <3 may serve as endoscopic goals of CRS treatment. These results provide guidance for using nasal endoscopy findings as a criterion of CRS disease control.
| Item Type: | Article |
|---|---|
| Additional Information: | Publisher Copyright: © 2025, International Rhinologic Society. All rights reserved. |
| Uncontrolled Keywords: | chronic rhinosinusitis,control,lund-kennedy score,nasal endoscopy,nasal polyp score,outcome measure,otorhinolaryngology ,/dk/atira/pure/subjectarea/asjc/2700/2733 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 04 Mar 2025 16:30 |
| Last Modified: | 10 Mar 2025 13:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/98668 |
| DOI: | 10.4193/Rhin24.291 |
Downloads
Downloads per month over past year
Actions (login required)
 |
View Item |