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ToolsHickling, Lauren M., Allani, Selsebil, Cella, Matteo and Scott, Whitney (2024) A systematic review with meta-analyses of the association between stigma and chronic pain outcomes. Pain, 165 (8). pp. 1689-1701. ISSN 0304-3959
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Abstract
Stigma is common in people experiencing chronic pain and there are indications that it may adversely affect pain outcomes. However, to date, there is no systematic review exploring the impact of stigma on chronic pain-related outcomes. This systematic review and meta-analysis aimed to examine the association between stigma and key chronic pain outcomes and differences in stigma between pain conditions. Seven databases were searched for studies reporting a measure of association between stigma and at least one pain outcome in adults with chronic pain. Studies were screened by 2 independent researchers. Nineteen studies met eligibility criteria and data were extracted, quality-assessed, and narratively synthesised and meta-analysed where possible. Meta-analyses of bivariate cross-sectional correlations demonstrated significant positive correlations between stigma and pain intensity, disability, and depression, with small to moderate effects. Data from 2 prospective studies and those only reporting multivariate analyses that were not included in meta-analyses further supported these findings. There was some evidence that individuals who experience pain conditions with less clear pathophysiology may report greater stigma, although more research is needed. The review highlights that there is a growing number of studies on stigma in the pain field showing an adverse association between stigma and chronic pain outcomes.
| Item Type: | Article |
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| Additional Information: | Acknowledgements: W. Scott is partly funded through the National Institute for Health and Care Research (NIHR) Biomedical Research Centre at the South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health and Social Care. W. Scott also receives funding from a Medical Research Council and Versus Arthritis consortium grant as part of the Advanced Pain Discovery Platform (MR/W002388/1); this funding is unrelated to the current work. W. Scott has received travel support to attend scientific meetings of the British Pain Society and the Neuropathic Pain Special Interest Group of the International Association for the Study of Pain. The authors report no further conflicts of interest. The extracted data and code for the meta-analyses will be available through contacting the corresponding author. |
| Uncontrolled Keywords: | chronic pain,meta-analysis,stigma,systematic review,clinical neurology,neurology,anesthesiology and pain medicine ,/dk/atira/pure/subjectarea/asjc/2700/2728 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 04 Mar 2025 15:30 |
| Last Modified: | 10 Mar 2025 13:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/98661 |
| DOI: | 10.1097/j.pain.0000000000003243 |
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