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ToolsValmiki, Maya, Teo, Stephen Ping, de Resende, Pedro Ernesto, Gibbons, Simon and Ganesan, A. (2024) Caudiquinol: A meroterpenoid with an intact C20 geranylgeranyl chain isolated from Garcinia caudiculata. Molecules, 29 (15). ISSN 1420-3049
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Abstract
The tropical Garcinia genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Garcinia caudiculata Ridl. from the island of Borneo. Fractionation, purification, and structure elucidation by MS and NMR resulted in the discovery of two meroterpenoids. One was a benzofuranone lactone previously isolated from Iryanthera grandis and Rhus chinensis, and the second was a new hydroquinone methyl ester that we named caudiquinol. Both natural products are rare examples of plant meroterpenoids with an intact geranylgeranyl chain.
| Item Type: | Article |
|---|---|
| Additional Information: | Data Availability Statement: The data are contained within this article and the Supplementary Materials. Funding Information: This research received no external funding. We thank the University of East Anglia for awarding a studentship to M.V. |
| Uncontrolled Keywords: | garcinia species,hydroquinones,meroterpenoids,natural products,analytical chemistry,chemistry (miscellaneous),molecular medicine,pharmaceutical science,drug discovery,physical and theoretical chemistry,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1600/1602 |
| Faculty \ School: | Faculty of Science > School of Chemistry, Pharmacy and Pharmacology Faculty of Science > School of Pharmacy (former - to 2024) |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 10 Jan 2025 01:00 |
| Last Modified: | 28 Jan 2025 23:47 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/98136 |
| DOI: |
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