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Etherington, Graham J., Gil, Elisa Gomez, Haerty, Wilfried 
ORCID: https://orcid.org/0000-0003-0111-191X, Oliferenko, Snezhana and Nieduszynski, Conrad A. ORCID: https://orcid.org/0000-0003-2001-076X
(2024)
Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast.
Yeast, 41 (3).
pp. 95-107.
ISSN 0749-503X
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Abstract
The fission yeast species Schizosaccharomyces japonicus is currently divided into two varieties—S. japonicus var. japonicus and S. japonicus var. versatilis. Here we examine the var. versatilis isolate CBS5679. The CBS5679 genome shows 88% identity to the reference genome of S. japonicus var. japonicus at the coding sequence level, with phylogenetic analyses suggesting that it has split from the S. japonicus lineage 25 million years ago. The CBS5679 genome contains a reciprocal translocation between chromosomes 1 and 2, together with several large inversions. The products of genes linked to the major translocation are associated with ‘metabolism’ and ‘cellular assembly’ ontology terms. We further show that CBS5679 does not generate viable progeny with the reference strain of S. japonicus. Although CBS5679 shares closer similarity to the ‘type’ strain of var. versatilis as compared to S. japonicus, it is not identical to the type strain, suggesting population structure within var. versatilis. We recommend that the taxonomic status of S. japonicus var. versatilis is raised, with it being treated as a separate species, Schizosaccharomyces versatilis.
| Item Type: | Article |
|---|---|
| Additional Information: | data Availability Statement: The data that support the findings of this study are openly available in ENA at https://www.ebi.ac.uk/ena/, reference number PRJEB63472. The genome assembly for S. versatilis can be found under ENA Project PRJEB63472. The final chromosome scale assembly can be found at NCBI with an accession number of GCA_958267425. Funding Information: G. J. E., W. H., and C. A. N. acknowledge funding from the from the Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation, Core Capability Grant BB/CCG1720/1. This research was supported in part by the NBI Research Computing through use of the High-Performance Computing system and Isilon storage. E. G. G is funded through a long-term EMBO postdoctoral fellowship (ALTF 712-2022). Work in S.O. lab is supported by the Wellcome Trust Investigator Award in Science (220790/Z/20/Z) and BBSRC (BB/T000481/1) to Snezhana Oliferenko. |
| Uncontrolled Keywords: | adaptation,evolution,fission yeast,schizosaccharomyces versatilis,taxonomy,biotechnology,bioengineering,biochemistry,applied microbiology and biotechnology,genetics ,/dk/atira/pure/subjectarea/asjc/1300/1305 |
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 22 Oct 2024 11:30 |
| Last Modified: | 18 Dec 2024 01:38 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/97103 |
| DOI: | 10.1002/yea.3919 |
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