Anti-N-methyl-D-aspartate receptor antibody encephalitis: Post-acute neuropsychological consequences and rehabilitation in adolescence

Harter, Catherine and Gracey, Fergus ORCID: https://orcid.org/0000-0002-1416-7894 (2023) Anti-N-methyl-D-aspartate receptor antibody encephalitis: Post-acute neuropsychological consequences and rehabilitation in adolescence. In: Rare Conditions, Diagnostic Challenges, and Controversies in Clinical Neuropsychology. Taylor and Francis, pp. 110-129. ISBN 9781032132259

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Abstract

We present a case of a teenager (Laura) with anti-NMDA receptor encephalitis who was seen post-acute illness within an interdisciplinary community paediatric neuropsychological rehabilitation centre. Following a review of the key literature summarising this condition, illness trajectory, and outcomes, we describe Laura's clinical presentation and the prolonged route to appropriate services and treatment. We describe our initial and follow-up assessment in order to track her recovery and put in place community-based rehabilitation. We also discuss the dilemma clinicians face in timing the administration of standard neuropsychological assessment in individuals where presentation, outcome, and recovery, including valid test batteries for repeated measurement, are less clearly defined. We include a review of the broader confounds to recovery, consideration of repeated and long-term neuropsychological assessment to facilitate a resumption of normal life including school and community relationships. Finally, we discuss the need to consider secondary consequences, especially in the developmental context of this rare condition; including lingering illness, trauma, and the impact of interruptions to key periods of development. In sharing this case we hope to raise awareness of this condition to aid rapid identification and treatment, including the need for longer-term support where needed.

Item Type: Book Section
Additional Information: Publisher Copyright: © 2023 selection and editorial matter, Jessica Fish, Shai Betteridge, and Barbara A. Wilson; individual chapters, the contributors.
Uncontrolled Keywords: psychology(all),medicine(all) ,/dk/atira/pure/subjectarea/asjc/3200
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
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Depositing User: LivePure Connector
Date Deposited: 17 Sep 2024 14:30
Last Modified: 24 Sep 2024 08:28
URI: https://ueaeprints.uea.ac.uk/id/eprint/96760
DOI: 10.4324/9781003228226-10

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