Proline 4-hydroxylase: Stereochemical course of the reaction

Baldwin, Jack E., Field, Robert A., Lawrence, Christopher C., Merritt, Kirsten D. and Schofield, Christopher J. (1993) Proline 4-hydroxylase: Stereochemical course of the reaction. Tetrahedron Letters, 34 (46). pp. 7489-7492. ISSN 0040-4039

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Abstract

The stereochemical course of the hydroxylation of (S)-proline by proline 4-hydroxylase from Streptomyces griseoviridus P8648 has been investigated using (2S, 4S)-[4-2H1]-proline and (2S, 4R)-[4-2H1]-proline and found to occur with retention of stereochemistry at C-4 of proline.

Item Type: Article
Uncontrolled Keywords: biochemistry,drug discovery,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1300/1303
Faculty \ School: Faculty of Science > School of Chemistry, Pharmacy and Pharmacology
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Depositing User: LivePure Connector
Date Deposited: 11 Sep 2024 14:30
Last Modified: 28 Jan 2025 23:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/96723
DOI:

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