Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

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Kirton, Eirene H. M., Tughan, Gary, Morris, Russell E. and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2004) Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines. Tetrahedron Letters, 45 (4). pp. 853-855. ISSN 0040-4039

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Abstract

Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction.

Item Type:	Article
Additional Information:	Funding Information: This study was supported by EPSRC and GSK (CASE award to E.H.M.K.).
Uncontrolled Keywords:	biochemistry,drug discovery,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1300/1303
Faculty \ School:	Faculty of Science > School of Chemistry, Pharmacy and Pharmacology
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	10 Sep 2024 12:30
Last Modified:	25 Sep 2024 18:08
URI:	https://ueaeprints.uea.ac.uk/id/eprint/96652
DOI:	10.1016/j.tetlet.2003.11.021

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