The saponins-polar isoprenoids with important and diverse biological activities

Osbourn, Anne, Goss, Rebecca J.M. and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2011) The saponins-polar isoprenoids with important and diverse biological activities. Natural Product Reports, 28 (7). pp. 1261-1268. ISSN 0265-0568

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Abstract

Saponins are polar molecules that consist of a triterpene or steroid aglycone with one or more sugar chains. They are one of the most numerous and diverse groups of plant natural products. These molecules have important ecological and agronomic functions, contributing to pest and pathogen resistance and to food quality in crop plants. They also have a wide range of commercial applications in the food, cosmetics and pharmaceutical sectors. Although primarily found in plants, saponins are produced by certain other organisms, including starfish and sea cucumbers. The underexplored biodiversity of this class of natural products is likely to prove to be a vital resource for discovery of high-value compounds. This review will focus on the biological activity of some of the best-studied examples of saponins, on the relationship between structure and function, and on prospects for synthesis of "designer" saponins.

Item Type: Article
Uncontrolled Keywords: biochemistry,drug discovery,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1300/1303
Faculty \ School:
Faculty of Science > School of Biological Sciences
Faculty of Science
Faculty of Science > School of Chemistry (former - to 2024)
Faculty of Science > School of Chemistry, Pharmacy and Pharmacology
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 06 Sep 2024 12:33
Last Modified: 25 Sep 2024 18:07
URI: https://ueaeprints.uea.ac.uk/id/eprint/96578
DOI: 10.1039/c1np00015b

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