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O'Neill, Ellis C. and Field, Robert A. 
ORCID: https://orcid.org/0000-0001-8574-0275
(2015)
Enzymatic synthesis using glycoside phosphorylases.
Carbohydrate Research, 403.
pp. 23-37.
ISSN 0008-6215
Abstract
Carbohydrate phosphorylases are readily accessible but under-explored catalysts for glycoside synthesis. Their use of accessible and relatively stable sugar phosphates as donor substrates underlies their potential. A wide range of these enzymes has been reported of late, displaying a range of preferences for sugar donors, acceptors and glycosidic linkages. This has allowed this class of enzymes to be used in the synthesis of diverse carbohydrate structures, including at the industrial scale. As more phosphorylase enzymes are discovered, access to further difficult to synthesise glycosides will be enabled. Herein we review reported phosphorylase enzymes and the glycoside products that they have been used to synthesise.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: Studies in the authors’ laboratory are supported by the UK BBSRC Institute Strategic Programme Grant on Understanding and Exploiting Metabolism (MET) [ BB/J004561/1 ] and the John Innes Foundation. Publisher Copyright: © 2014 The Authors. Published by Elsevier Ltd. |
| Uncontrolled Keywords: | glycosides,phosphorylases,synthesis,analytical chemistry,biochemistry,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1600/1602 |
| Faculty \ School: | Faculty of Science > School of Chemistry, Pharmacy and Pharmacology |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 04 Sep 2024 13:35 |
| Last Modified: | 25 Sep 2024 18:06 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/96533 |
| DOI: | 10.1016/j.carres.2014.06.010 |
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