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Charoenwongpaiboon, Thanapon, Wangpaiboon, Karan, Panpetch, Pawinee, Field, Robert A. 
ORCID: https://orcid.org/0000-0001-8574-0275, Barclay, J. Elaine, Pichyangkura, Rath and Kuttiyawong, Kamontip
(2019)
Temperature-dependent inulin nanoparticles synthesized by Lactobacillus reuteri 121 inulosucrase and complex formation with flavonoids.
Carbohydrate Polymers, 223.
ISSN 0144-8617
Abstract
Inulin nanoparticles (INNPs) are a biocompatible material which has a potential application for enhancing solubility and preventing degradation of compounds. In this work, we demonstrated that INNPs could be synthesized from sucrose using inulosucrase from Lactobacillus reuteri 121. Noticeably, dynamic light scattering (DLS) analysis showed that the derived INNPs exhibited uniformity in size, which was easily controlled by the reaction temperature. The effect of enzyme and sucrose concentration, as well as reaction time, was explored. Moreover, the solubility of INNPs in various organic solvents was also investigated, and we found that the INNPs were freely regenerated in water even though they had precipitated by organic solvents. Essentially, we demonstrated that the derived INNPs could be applied for flavonoid encapsulation. The solubility and stability of quercetin and fisetin in the INNPs complexes was higher than those of free compounds. These results make the INNPs very promising for many applications.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: TC is grateful for scholarship support from Science Achievement Scholarship of Thailand (SAST) . KK was partially supported by the Thailand Research Fund (MRG5480232) and Faculty of Liberal Arts and Science, Kasetsart University, Kamphaeng Saen Campus (year 2016). Research at the JIC is supported by the UK BBSRC Institute Strategic Program on Molecules from Nature (MfN) [BB/PO12523/1] and the John Innes Foundation. |
| Uncontrolled Keywords: | encapsulation,flavonoids,inulin nanoparticles,inulosucrase,organic chemistry,polymers and plastics,materials chemistry ,/dk/atira/pure/subjectarea/asjc/1600/1605 |
| Faculty \ School: | Faculty of Science > School of Chemistry, Pharmacy and Pharmacology |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 02 Sep 2024 15:30 |
| Last Modified: | 25 Sep 2024 18:05 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/96443 |
| DOI: | 10.1016/j.carbpol.2019.115044 |
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