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Loades, Maria E., St Clair, Michelle C., Orchard, Faith 
ORCID: https://orcid.org/0000-0002-5324-5007, Goodyer, Ian and Reynolds, Shirley
and
IMPACT Consortium
(2022)
Depression symptom clusters in adolescents: A latent class analysis in a clinical sample.
Psychotherapy Research, 32 (7).
pp. 860-873.
ISSN 1050-3307
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Abstract
Background: Major depression is clinically heterogeneous. We aimed to identify classes of depressed adolescents with different symptom presentations and examine if these were differentially associated with illness severity, functioning, engagement with treatment, and clinical outcomes. Method: Baseline depression symptoms of 454 depressed adolescents (age 11–17) from the IMPACT trial were subjected to latent class analysis. We compared classes on self-reported symptoms and social impairment at baseline and follow-up and their engagement in treatment. Results: We identified three classes of participants which differed in the number and pattern of depression symptoms; Class 1—Severe- (37.2%)—endorsed almost all symptoms and were most functionally impaired; Class 2—Moderate- (41.9%)—endorsed fewer symptoms with high suicidal ideation, self-harm, and worthlessness; Class 3—Somatic (20.9%)—endorsed fewest symptoms, with high somatic symptoms. Groups did not differ on engagement, therapeutic alliance, or post-treatment symptom reduction. Adolescents in the severe and moderate subgroups reported symptom reductions after treatment ended, whilst those in the somatic subgroup did not. Conclusions: At presentation, high somatic features in depressed adolescents, rather than severity, or impairment levels, may indicate lower liability for responding to psychological treatment.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: Dr Loades is funded by the National Institute for Health Research (NIHR Doctoral Research Fellowship, DRF-2016-09-021). This report is independent research. The views expressed in this publication are those of the authors(s) and not necessarily those of the NHS, NIHR or the Department of Health and Social Care. |
| Uncontrolled Keywords: | adolescents,depression,latent class analysis,subtyping,symptoms,clinical psychology,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/3200/3203 |
| Faculty \ School: | Faculty of Social Sciences > School of Psychology Faculty of Medicine and Health Sciences > Norwich Medical School |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 22 Aug 2024 09:30 |
| Last Modified: | 18 Nov 2024 00:56 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/96305 |
| DOI: | 10.1080/10503307.2022.2030498 |
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