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Yeung, Andy Wai Kan, El-Demerdash, Amr 
ORCID: https://orcid.org/0000-0001-6459-2955, Berindan-Neagoe, Ioana, Atanasov, Atanas G. and Ho, Yuh Shan
(2018)
Molecular responses of cancers by natural products: Modifications of autophagy revealed by literature analysis.
Critical Reviews in Oncogenesis, 23 (5-6).
pp. 347-370.
ISSN 0893-9675
Abstract
Although numerous bibliometric studies have examined various aspects of cancer research, the landscape of scientific studies focusing on natural products in cancer research has not been characterized. Using the Web of Science Core Collection online database, we identify and analyze scientific articles on natural products in cancer-related research. English is the language of publication for 99% of articles. In general, annual citation count of an article increases quickly after publication, reaches a plateau in the second year, stays in this plateau for 10 yr, and then begins to fall. The five most contributing journal categories are medicinal chemistry, contributing the most at 1890 articles (24% of 8012 articles); oncology (20%, with 1572 articles); pharmacology and pharmacy (19%, with 1557); biochemistry and molecular biology (15%, with 1225); and plant sciences (11%, with 883 articles). The United States and Spain yield a larger number of articles with high average citations, and China has been increasing since 2009. Apoptosis and cytotoxicity are the two most-frequently used keywords. Effects of natural products on autophagy with a relevance to cancer are mentioned in 69 publications. Our literature analysis reveals a dynamically evolving landscape and an increasing volume of research investigations that are focused on the study of natural products in the context of cancer. Curcumin, flavonoids, and resveratrol are the most-frequently mentioned natural products. Cancer of the breast, prostate, and colon are the most-frequently mentioned cancers.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: A.G.A. acknowledges the support of Poland’s KNOW (Leading National Research Centre) Scientific Consortium, Healthy Animal—Safe Food, in the division of the Ministry of Science and Higher Education (grant no. 05-1/KNOW2/2015). Publisher Copyright: © 2018 by Begell House, Inc. |
| Uncontrolled Keywords: | autophagy,bibliometric,cancer,citation analysis,jasplakinolide,natural product,phytochemical,cancer research,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/1300/1306 |
| Faculty \ School: | Faculty of Science > School of Pharmacy (former - to 2024) |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 05 Aug 2024 11:33 |
| Last Modified: | 12 Aug 2024 09:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/96143 |
| DOI: | 10.1615/CritRevOncog.2018027566 |
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