Chemical diversity and biological activities of phaeosphaeria fungi genus:A systematic review

El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 (2018) Chemical diversity and biological activities of phaeosphaeria fungi genus:A systematic review. Journal of Fungi, 4 (4). ISSN 2309-608X

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Abstract

Microbial natural products (MNPs) have been identified as important hotspots and effective sources for drug lead discovery. The genus Phaeosphaeria (family: Phaeosphaeriaceae, order: Pleosporales), in particular, has produced divergent chemical structures, including pyrazine alkaloids, isocoumarins, perylenequinones, anthraquinones, diterpenes, and cyclic peptides, which display a wide scope of biological potentialities. This contribution comprehensively highlights, over the period 1974–2018, the chemistry and biology of the isolated natural products from the micro-filamentous Phaeosphaeria fungi genus. A list of 71 compounds, with structural and biological diversities, were gathered into 5 main groups.

Item Type: Article
Additional Information: Funding Information: Amr El-Demerdash is grateful to Soizic Prado; head of the fungal natural products research team, French National Museum of Natural History, CNRS-MNHN, Sorbonne Universities Paris, for hosting, supervising, and providing research tools. Publisher Copyright: © 2018 by the author. Licensee MDPI, Basel, Switzerland.
Uncontrolled Keywords: anthraquinones,bioactivities,cyclic peptides,isocoumarins,perylenequinones,phaeosphaeria,polyketides,pyrazine alkaloids,ecology, evolution, behavior and systematics,plant science,microbiology (medical) ,/dk/atira/pure/subjectarea/asjc/1100/1105
Faculty \ School: Faculty of Science > School of Pharmacy (former - to 2024)
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Depositing User: LivePure Connector
Date Deposited: 05 Aug 2024 11:33
Last Modified: 11 Aug 2024 05:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/96141
DOI: 10.3390/jof4040130

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