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El-Demerdash, Amr 
ORCID: https://orcid.org/0000-0001-6459-2955, Kumla, Decha and Kijjoa, Anake
(2020)
Chemical diversity and biological activities of meroterpenoids from marine derived-fungi:A comprehensive update.
Marine Drugs, 18 (6).
ISSN 1660-3397
Abstract
Meroterpenoids are a class of hybrid natural products, partially derived from a mixed terpenoid pathway. They possess remarkable structural features and relevant biological and pharmacological activities. Marine-derived fungi are a rich source of meroterpenoids featuring structural diversity varying from simple to complex molecular architectures. A combination of a structural variability and their myriad of bioactivities makes meroterpenoids an interesting class of naturally occurring compounds for chemical and pharmacological investigation. In this review, a comprehensive literature survey covering the period of 2009–2019, with 86 references, is presented focusing on chemistry and biological activities of various classes of meroterpenoids isolated from fungi obtained from different marine hosts and environments.
| Item Type: | Article |
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| Additional Information: | Funding Information: Funding: This work was partially supported through national funds provided by FCT/MCTES-Foundation for Science and Technology from the Minister of Science, Technology and Higher Education (PIDDAC) and European Regional Development Fund (ERDF) through the COMPETE-Programa Operacional Factores de Competitividade (POFC) programme, under the projects PTDC/MAR-BIO/4694/2014 (reference POCI-01-0145-FEDER-016790), POCI-01-0145-FEDER-028736 and by national fund through FCT-Foundation for Sciences and Technology within the scope of UIDB/04423/2020 and UIDP/04423/2020. Funding Information: Acknowledgments: Amr El-Demerdash thanks the John Innes Centre, Department of Metabolic Biology of the Norwich Research Park, UK, for a postdoctoral scholarship. Decha Kumla thanks the Alfabet Project of the Erasmus Mundus for a PhD scholarship to the University of Porto. Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution |
| Uncontrolled Keywords: | anti-inflammatory,antibacterial,biological activities,cytotoxicity,marine-derived fungi,meroterpenoids,pharmaceutical science,drug discovery,pharmacology, toxicology and pharmaceutics (miscellaneous),sdg 14 - life below water ,/dk/atira/pure/subjectarea/asjc/3000/3003 |
| Faculty \ School: | Faculty of Science > School of Pharmacy (former - to 2024) |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 05 Aug 2024 11:32 |
| Last Modified: | 25 Sep 2024 17:59 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/96133 |
| DOI: | 10.3390/md18060317 |
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