Catalogue of antimicrobial resistance genes in species of Bacillus used to produce food enzymes and feed additives

Peluso, Silvia, Aguilera-Gómez, Margarita, Bortolaia, Valeria, Catania, Francesco, Cocconcelli, Pier Sandro, Herman, Lieve, Moxon, Simon ORCID: https://orcid.org/0000-0003-4644-1816, Vernis, Laurence, Iacono, Giovanni, Lunardi, Simone, Pettenati, Elisa, Gallo, Arianna and Aguilera, Jaime and European Food Safety Authority (EFSA) (2024) Catalogue of antimicrobial resistance genes in species of Bacillus used to produce food enzymes and feed additives. EFSA Journal, 21 (7). ISSN 1831-4732

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Abstract

A key step in the characterisation of bacterial strains used in the food and feed chain is the identification of antimicrobial resistance (AMR) genes in their genomes. The presence of acquired AMR genes influences important aspects of the risk assessment, such as the applicability of the qualified presumption of safety (QPS) approach, which can have a direct impact on the data requirements. Aiming to implement the EFSA approach to discriminate between ‘intrinsic’ and ‘acquired’ AMR genes, a bioinformatics pipeline was developed and applied to the species of the genus Bacillus that are most frequently subjects of applications for regulated products submitted to EFSA. The results are presented as a catalogue of genes indicating their abundance and distribution among complete and confirmed genomes publicly available for each species. The results of this work are aimed to support the evaluation of AMR genes in a consistent and harmonised way.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Biological Sciences
Depositing User:	LivePure Connector
Date Deposited:	19 Jul 2024 10:32
Last Modified:	10 Aug 2024 00:33
URI:	https://ueaeprints.uea.ac.uk/id/eprint/95963
DOI:	10.2903/sp.efsa.2024.EN-8931

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