Fatal acute haemopericardium associated with rivaroxaban in a patient with non-valvular atrial fibrillation

Omer, Siddiq, Magezi, Frederick, Patel, Martyn and Alsawaf, Ali (2019) Fatal acute haemopericardium associated with rivaroxaban in a patient with non-valvular atrial fibrillation. Age and Ageing, 48 (5). 764–766. ISSN 0002-0729

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Abstract

An 82-year-old female was admitted with chest pain and non-specific T wave changes on her ECG. After 72 hours of conservative management she deteriorated with non-specific symptoms including nausea and a single episode of vomiting. Abdominal and Chest X-rays were unremarkable, blood tests showed worsening Acute Kidney Injury (AKI) on Chronic Kidney Disease (CKD); and raised C-Reactive Protein (CRP) with no obvious symptoms or focus of infection. She rapidly deteriorated going into asystole cardiac arrest and attempts at resuscitation failed. Post-mortem examination suggested the most likely cause of death was acute spontaneous Haemopericardium due to Rivaroxaban therapy which she was on for non-valvular Atrial Fibrillation (AF). We believe that this might be the first reported mortality with Rivaroxaban-associated spontaneous haemopericardium in the UK.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Mental Health and Social Care (fka Lifespan Health)
Depositing User:	LivePure Connector
Date Deposited:	13 Jun 2024 13:30
Last Modified:	13 Oct 2025 05:33
URI:	https://ueaeprints.uea.ac.uk/id/eprint/95598
DOI:	10.1093/ageing/afz070

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