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Chevalier, Stephane and Blow, J. Julian 
ORCID: https://orcid.org/0000-0002-9524-5849
(1996)
Cell cycle control of replication initiation in eukaryotes.
Current Opinion in Cell Biology, 8 (6).
pp. 815-821.
ISSN 0955-0674
Abstract
Studies on the initiation of DNA replication in eukaryotes have progressed recently through different approaches that promise to converge. Proteins interacting with the origin recognition complex form a prereplicative complex early in the cell cycle. The regulation of the binding of MCM/P1 proteins to chromatin plays a key role in the replication licensing system which prevents re-replication in a single cell cycle. Cyclin-dependent kinases provide an overall control of the cell cycle by stimulating S-phase entry and possibly by preventing re-establishment of prereplicative complexes in G2 phase.
| Item Type: | Article |
|---|---|
| Faculty \ School: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 11 Jun 2024 09:30 |
| Last Modified: | 25 Sep 2024 17:52 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/95538 |
| DOI: | 10.1016/S0955-0674(96)80082-2 |
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