Tools
Tools
Herr, A. J., Jensen, M. B., Dalmay, T. 
ORCID: https://orcid.org/0000-0003-1492-5429 and Baulcombe, D. C.
(2005)
RNA polymerase IV directs silencing of endogenous DNA.
Science, 308 (5718).
pp. 118-120.
ISSN 0036-8075
Abstract
Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition to the well-known DNA-dependent RNA polymerases I, II, and III. By mutation of the two largest subunits (NRPD1a and NRPD2), we show that Pol IV silences certain transposons and repetitive DNA in a short interfering RNA pathway involving RNA-dependent RNA polymerase 2 and Dicer-like 3. The existence of this distinct silencing polymerase may explain the paradoxical involvement of an RNA silencing pathway in maintenance of transcriptional silencing.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| UEA Research Groups: | Faculty of Science > Research Groups > Plant Sciences |
| Depositing User: | EPrints Services |
| Date Deposited: | 01 Oct 2010 13:37 |
| Last Modified: | 24 Sep 2024 09:57 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/955 |
| DOI: | 10.1126/science.1106910 |
Actions (login required)
 |
View Item |