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Blow, J. Julian 
ORCID: https://orcid.org/0000-0002-9524-5849 and Tanaka, Tomoyuki U.
(2005)
The chromosome cycle: coordinating replication and segregation.
EMBO Reports, 6 (11).
pp. 1028-1034.
ISSN 1469-221X
Abstract
During the cell-division cycle, chromosomal DNA must initially be precisely duplicated and then correctly segregated to daughter cells. The accuracy of these two events is maintained by two interlinked cycles: the replication licensing cycle, which ensures precise duplication of DNA, and the cohesion cycle, which ensures correct segregation. Here we provide a general overview of how these two systems are coordinated to maintain genetic stability during the cell cycle.
| Item Type: | Article |
|---|---|
| Additional Information: | Second in the Cycles review series |
| Uncontrolled Keywords: | cell cycle,cohesion,dna replication,replication licensing |
| Faculty \ School: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 10 Jun 2024 15:31 |
| Last Modified: | 25 Sep 2024 17:53 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/95481 |
| DOI: | 10.1038/sj.embor.7400557 |
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