Defects in the origin licensing checkpoint stresses cells exiting G0

Blow, J. Julian ORCID: https://orcid.org/0000-0002-9524-5849 (2019) Defects in the origin licensing checkpoint stresses cells exiting G0. Journal of Cell Biology, 218 (7). pp. 2080-2081. ISSN 0021-9525

Preview

PDF (jcb_201905181) - Published Version Available under License Creative Commons Attribution Non-commercial Share Alike. Download (706kB) | Preview

Abstract

The full licensing of replication origins in late G1 is normally enforced by the licensing checkpoint. In this issue, Matson et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902143) show that this checkpoint is inoperative in cells exiting from G0, resulting in incomplete origin licensing and consequent replicative stress.

Item Type:	Article
Additional Information:	Funding: Wellcome Trust WT096598MA
Faculty \ School:
Depositing User:	LivePure Connector
Date Deposited:	10 Jun 2024 14:30
Last Modified:	23 Jul 2024 02:22
URI:	https://ueaeprints.uea.ac.uk/id/eprint/95454
DOI:	10.1083/jcb.201905181

Downloads

Actions (login required)

View Item