Defects in the origin licensing checkpoint stresses cells exiting G0

Blow, J. Julian (2019) Defects in the origin licensing checkpoint stresses cells exiting G0. Journal of Cell Biology, 218 (7). pp. 2080-2081. ISSN 0021-9525

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Abstract

The full licensing of replication origins in late G1 is normally enforced by the licensing checkpoint. In this issue, Matson et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902143) show that this checkpoint is inoperative in cells exiting from G0, resulting in incomplete origin licensing and consequent replicative stress.

Item Type:	Article
Additional Information:	Funding: Wellcome Trust WT096598MA
Faculty \ School:
Depositing User:	LivePure Connector
Date Deposited:	10 Jun 2024 14:30
Last Modified:	10 Jun 2024 14:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/95454
DOI:	10.1083/jcb.201905181

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