A role for dormant origins in tumor suppression

Klotz-Noack, Kathleen and Blow, J. Julian (2011) A role for dormant origins in tumor suppression. Molecular Cell, 41 (5). pp. 495-496. ISSN 1097-2765

Full text not available from this repository. (Request a copy)

Abstract

In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

Item Type:	Article
Uncontrolled Keywords:	replicative stress,excess mcm2-7,cancer,mice,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:
Depositing User:	LivePure Connector
Date Deposited:	10 Jun 2024 10:31
Last Modified:	13 Oct 2025 04:34
URI:	https://ueaeprints.uea.ac.uk/id/eprint/95440
DOI:	10.1016/j.molcel.2011.02.014

Actions (login required)

View Item