Comprehensive geriatric assessment for people with both COPD and frailty starting pulmonary rehabilitation: a mixed-methods feasibility trial

Brighton, Lisa Jane, Evans, Catherine J., Farquhar, Morag ORCID: https://orcid.org/0000-0001-7991-7679, Bristowe, Katherine, Kata, Aleksandra, Higman, Jade, Ogden, Margaret, Nolan, Claire, Yi, Deokhee, Gao, Wei, Koulopoulou, Maria, Hasan, Sharmeen, Ingram, Karen, Clarke, Stuart, Parmar, Kishan, Baldwin, Eleni, Steves, Claire J., Man, William D.-C. and Maddocks, Matthew (2024) Comprehensive geriatric assessment for people with both COPD and frailty starting pulmonary rehabilitation: a mixed-methods feasibility trial. ERJ Open Research, 10 (4). ISSN 2312-0541

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Abstract

Introduction Many people with COPD experience frailty. Frailty increases risk of poor health outcomes, including non-completion of pulmonary rehabilitation. Integrated approaches to support people with COPD and frailty throughout and following rehabilitation are indicated. The aim of the present study was to determine the feasibility of conducting a randomised controlled trial of integrating comprehensive geriatric assessment (CGA) for people with COPD and frailty starting pulmonary rehabilitation. Methods A multicentre mixed-methods randomised controlled feasibility trial (“Breathe Plus”; ISRCTN13051922) was carried out. People with COPD, aged ⩾50 years, Clinical Frailty Scale ⩾5 and referred for pulmonary rehabilitation were randomised 1:1 to usual pulmonary rehabilitation, or pulmonary rehabilitation plus CGA. Remote intervention delivery was used during COVID-19 restrictions. Outcomes (physical, psychosocial, service use) were measured at baseline, 90 and 180 days, alongside process data and qualitative interviews. Results Recruitment stopped at 31 participants (mean±SD age 72.4±10.1 years, 68% Medical Research Council Dyspnoea Scale 4–5), due to COVID-19-related disruptions. Recruitment (46% eligible recruited) and retention (87% at 90-and 180-day follow-up) were acceptable. CGAs occurred on average 60.5 days post-randomisation (range 8–129) and prompted 46 individual care recommendations (median 3 per participant, range 0–12), 65% of which were implemented during follow-up. The most common domains addressed during CGA were nutrition and cardiovascular health. Participants valued the holistic approach of CGA but questioned the optimal time to introduce it. Conclusion Integrating CGA alongside pulmonary rehabilitation is feasible and identifies unmet multidimensional need in people with COPD and frailty. Given challenges around timing and inclusivity, the integration of geriatric and respiratory care should not be limited to rehabilitation services.

Item Type: Article
Additional Information: Support statement: This project was funded by a National Institute for Health and Care Research (NIHR) Career Development Fellowship (CDF-2017-10-009) held by M. Maddocks. L.J. Brighton was funded by an ESRC Post-Doctoral Fellowship (ES/X005259/1). C.J. Evans was supported by a Health Education England/NIHR Senior Clinical Lectureship (ICA-SCL-2015-01-001). This research was supported by the NIHR Collaboration for Leadership in Applied Health Research and Care South London, now recommissioned as NIHR Applied Research Collaboration South London. This publication presents independent research funded by the NIHR. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, NIHR or the Department of Health and Social Care. Funding information for this article has been deposited with the Crossref Funder Registry.
Faculty \ School: Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Faculty of Medicine and Health Sciences > Research Groups > Health Promotion
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Depositing User: LivePure Connector
Date Deposited: 05 Apr 2024 10:32
Last Modified: 25 Sep 2024 17:45
URI: https://ueaeprints.uea.ac.uk/id/eprint/94839
DOI: 10.1183/23120541.00774-2023

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