Yersinia enterocolitica biovar 1A: An underappreciated potential pathogen in the food chain

Palau, Raphaёlle, Bloomfield, Samuel J., Jenkins, Claire, Greig, David R., Jorgensen, Frieda and Mather, Alison E. (2024) Yersinia enterocolitica biovar 1A: An underappreciated potential pathogen in the food chain. International Journal of Food Microbiology, 412. ISSN 0168-1605

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Abstract

Yersinia enterocolitica is an underreported cause of foodborne gastroenteritis. Little is known of the diversity of Y. enterocolitica isolated from food and which food commodities contribute to human disease. In this study, Y. enterocolitica was isolated from 37/50 raw chicken, 8/10 pork, 8/10 salmon and 1/10 leafy green samples collected at retail in the UK. Up to 10 presumptive Y. enterocolitica isolates per positive sample underwent whole genome sequencing (WGS) and were compared with publicly available genomes. In total, 207 Y. enterocolitica isolates were analyzed and belonged to 38 sequence types (STs). Up to five STs of Y. enterocolitica were isolated from individual food samples and isolates belonging to the same sample and ST differed by 0–74 single nucleotide polymorphisms (SNPs). Biotype was predicted for 205 (99 %) genomes that all belonged to biotype 1A, previously described as non-pathogenic. However, around half (51 %) of food samples contained isolates belonging to the same ST as previously isolated from UK human cases. The closest human-derived isolates shared between 17 and 7978 single nucleotide polymorphisms (SNPs) with the food isolates. Extensive food surveillance is required to determine what food sources are responsible for Y. enterocolitica infections and to re-examine the role of biotype 1A as a human pathogen.

Item Type:	Article
Additional Information:	Funding information: This project was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) Institute Strategic Programme Microbes in the Food Chain BB/R012504/1 and its constituent project BBS/E/F/000PR10348 (Theme 1, Epidemiology and Evolution of Pathogens in the Food Chain) and Food Standards Agency (FSA) project FS101185 through an FSA Fellowship to AEM. Further support was provided by BBSRC Institute Strategic Programme Microbes and Food Safety BB/X011011/1 and its constituent project BBS/E/F/000PR13634 (Theme 1, Microbial threats from foods in established and evolving food systems). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. Data availability: Genome data obtained as part of this study have been made publicly available on SRA.
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	LivePure Connector
Date Deposited:	03 Jan 2024 03:19
Last Modified:	06 Jun 2024 15:26
URI:	https://ueaeprints.uea.ac.uk/id/eprint/94055
DOI:	10.1016/j.ijfoodmicro.2023.110554

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