Generating cis-aza-diaryl and triaryl ethers via organoBrønsted acid catalysed aza-Darzens chemistry

Bew, Sean P. ORCID: https://orcid.org/0000-0002-9087-9463, Coles, Simon J., Pitak, Mateusz B., Klooster, Wim T., Ashford, Polly-Anna and Zdorichenko, Victor (2019) Generating cis-aza-diaryl and triaryl ethers via organoBrønsted acid catalysed aza-Darzens chemistry. Tetrahedron, 75 (42). ISSN 0040-4020

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Abstract

We report the efficient combination of SNAr and organic Brønsted acid catalysis protocols for the construction of cis-aziridine-derived biaryl and triaryl ethers. Using aza-Darzens chemistry mono-cis-aziridine-biaryl and bis-(cis-aziridine)-triaryl ethers have been generated; these motifs have significant potential as easily synthesised, functionalised precursors of a glycopeptide backbone.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Medicine and Health Sciences > Research Centres > Population Health
Related URLs:	https://www.sciencedirect.com/science/ar...
Depositing User:	LivePure Connector
Date Deposited:	12 Oct 2023 00:43
Last Modified:	30 Sep 2024 19:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/93271
DOI:	10.1016/j.tet.2019.130532

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